Associations between genetic variants of the insulin-like growth factor I (IGF-I) gene and growth traits in European sea bass (Dicentrarchus labrax, L.)

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dc.authorscopusid55907746500
dc.authorscopusid57200696504
dc.contributor.authorÖzcan Gökçek, Emel
dc.contributor.authorIşık, Raziye
dc.date.accessioned2022-05-11T14:07:11Z
dc.date.available2022-05-11T14:07:11Z
dc.date.issued2020
dc.departmentFakülteler, Ziraat Fakültesi, Tarımsal Biyoteknoloji Bölümü
dc.description.abstractThe IGF-I is a significant peptide hormone to cell growth, development, reproduction, and metabolism of teleost fish. This study was conducted to investigate the IGF-I gene polymorphism and to reveal the association between the genotypes of IGF-I gene and growth traits in 80 harvest size European sea bass (Dicentrarchus labrax, L.) reared in İzmir region of Turkey. The 821 bp long exon 1 and 5’ UTR regions of IGF-I gene were amplified, and PCR products were analyzed via DNA sequencing method. Two novel single nucleotide polymorphisms (SNPs) such as g.46672A > G and g.46749C > T in the 5’ UTR region of IGF-I gene in the European sea bass were detected for the first time with this study. Associations between the genotypes of IGF-I g.46749C > T locus and body weight were found statistically significant (p < 0.05). The genotypes of IGF-I g.46749C > T and g.46672A > G loci were found significantly associated with total length (p < 0.05). However, both loci did not show significant associations with body width. The studied gene region sequences were entered to NCBI GenBank database with the accession numbers: MK621680-MK621682. Thus, these polymorphisms have a significant effect on the body weight and total length which could be useful for sea bass selection and breeding for marker-assisted selection (MAS) program. © 2020, Springer Nature B.V.
dc.identifier.doi10.1007/s10695-020-00779-8
dc.identifier.endpage1138
dc.identifier.issn0920-1742
dc.identifier.issue3en_US
dc.identifier.pmid32140978
dc.identifier.scopus2-s2.0-85081609857
dc.identifier.scopusqualityQ1
dc.identifier.startpage1131
dc.identifier.urihttps://doi.org/10.1007/s10695-020-00779-8
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5001
dc.identifier.volume46
dc.identifier.wosWOS:000518425400001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorIşık, Raziye
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofFish Physiology and Biochemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectDNA sequencing
dc.subjectEuropean sea bass
dc.subjectIGF-I gene
dc.subjectPolymorphism
dc.subjectfish protein
dc.subjectsomatomedin C
dc.subjectanimal
dc.subjectbass
dc.subjectDNA sequence
dc.subjectgenetics
dc.subjectgenotype
dc.subjectgrowth, development and aging
dc.subjectmale
dc.subjectsingle nucleotide polymorphism
dc.subjectturkey (bird)
dc.subjectAnimals
dc.subjectBass
dc.subjectFish Proteins
dc.subjectGenotype
dc.subjectInsulin-Like Growth Factor I
dc.subjectMale
dc.subjectPolymorphism, Single Nucleotide
dc.subjectSequence Analysis, DNA
dc.subjectTurkey
dc.titleAssociations between genetic variants of the insulin-like growth factor I (IGF-I) gene and growth traits in European sea bass (Dicentrarchus labrax, L.)
dc.typeArticle

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