The efficacy of chloroquine treatment of Giardia duodenalis infection in calves

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dc.authorid0000-0001-7473-5163
dc.authorid0000-0002-8610-5174
dc.authorid0000-0002-5197-2403
dc.authorscopusid39361395500
dc.authorscopusid56045626500
dc.authorscopusid26532288600
dc.authorscopusid57189889312
dc.authorscopusid57188928984
dc.authorscopusid56543627500
dc.authorwosidBalıkçı, Canberk/ABG-8719-2020
dc.authorwosidAyan, Adnan/AAC-5226-2020
dc.authorwosidAkyildiz, Gurkan/AAE-8609-2019
dc.contributor.authorGültekin, Mehmet
dc.contributor.authorUral, K.
dc.contributor.authorAysul, Nuran
dc.contributor.authorAyan, A.
dc.contributor.authorBalıkçı, Canberk
dc.contributor.authorAkyıldız, Gürkan
dc.date.accessioned2022-05-11T14:28:35Z
dc.date.available2022-05-11T14:28:35Z
dc.date.issued2016
dc.departmentFakülteler, Fen Edebiyat Fakültesi, Biyoloji Bölümü
dc.description.abstractThe purpose of the present study was to evaluate the effect of chloroquine treatment on cyst excretion in calves naturally infected with Giardia duodenalis. The calves were randomly assigned into two groups based on placebo (group I, n=7 untreated control calves) or treatment (group II, n=7 calves treated orally with 2.5 mg/kg chloroquine twice daily for five consecutive days). The G. duodenalis isolates were identified by molecular characterization with beta-giardin nested PCR and gene sequence analysis as assemblage A3. Cyst excretion was determined on days 0, 3, 7 and 10, before and after treatment. Geometric means of the number of excreted cysts did not change significantly in the control group during the trial. The reduction in cyst excretion after chloroquine treatment was 99% on day 3 and 100% on days 7 and 10. Chloroquine treatment is most probatly practically applicable, relatively inexpensive and highly effective against giardiosis in calves.
dc.identifier.endpage341
dc.identifier.issn0303-9021
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85008449937
dc.identifier.scopusqualityQ4
dc.identifier.startpage335
dc.identifier.urihttps://hdl.handle.net/20.500.11776/6880
dc.identifier.volume85
dc.identifier.wosWOS:000391520000002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorAkyıldız, Gürkan
dc.language.isoen
dc.publisherUniv Ghent
dc.relation.ispartofVlaams Diergeneeskundig Tijdschrift
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectMolecular Characterization
dc.subjectCryptosporidium-Spp.
dc.subjectDairy-Cattle
dc.subjectFenbendazole Treatment
dc.subjectCyst Excretion
dc.subjectPrevalence
dc.subjectIdentification
dc.subjectAlbendazole
dc.subjectGenotypes
dc.subjectAntiprotozoal
dc.titleThe efficacy of chloroquine treatment of Giardia duodenalis infection in calves
dc.typeArticle

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