Comparison of the development of mouse embryos manipulatedwith different biopsy techniques

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dc.contributor.authorTaşkın, Ali Cihan
dc.contributor.authorAkkoç, Tolga
dc.contributor.authorSağırkaya, Hakan
dc.contributor.authorBağış, Haydar
dc.contributor.authorArat, Sezen
dc.date.accessioned2022-05-11T14:45:20Z
dc.date.available2022-05-11T14:45:20Z
dc.date.issued2016
dc.departmentFakülteler, Ziraat Fakültesi, Tarımsal Biyoteknoloji Bölümü
dc.description.abstractPreimplantation genetic diagnosis is the detection of inherited diseases and the sex of embryos before implantation in the practice of human medicine as well as in veterinary medicine. The introduction of experimental animal embryo biopsy techniques has been a milestone in the developmental process of preimplantation genetic diagnosis techniques. The aim of the present study was to evaluate in vivo and in vitro development of embryos after biopsy in an experimental mouse model and to perform comparisons across different biopsy techniques (blastomere biopsy and trophectoderm biopsy). At the end of the study, no significant difference was observed between the blastomere biopsy group and the control group in terms of in vitro development, embryo quality, and fetal development, whereas embryo quality and in vivo development were negatively affected in the trophectoderm biopsy group (P< 0.05).
dc.identifier.endpage162
dc.identifier.issn1300-0128
dc.identifier.issn1303-6181
dc.identifier.issue2en_US
dc.identifier.startpage157
dc.identifier.trdizinidTWpFek16UXlNZz09
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TWpFek16UXlNZz09
dc.identifier.urihttps://hdl.handle.net/20.500.11776/10011
dc.identifier.volume40
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorArat, Sezen
dc.language.isoen
dc.relation.ispartofTurkish Journal of Veterinary and Animal Sciences
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectZiraat Mühendisliği
dc.titleComparison of the development of mouse embryos manipulatedwith different biopsy techniques
dc.typeArticle

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