Histiocytic Sarcoma with Invasive Urothelial Carcinoma of Urinary Bladder

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dc.authorscopusid57720962100
dc.authorscopusid56904163300
dc.authorscopusid57720994600
dc.contributor.authorArslan, A.I.
dc.contributor.authorKarabağ, S.
dc.contributor.authorAkgül, Murat
dc.date.accessioned2023-04-20T08:04:16Z
dc.date.available2023-04-20T08:04:16Z
dc.date.issued2022
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Üroloji Ana Bilim Dalı
dc.description.abstractWe report a rare case of histiocytic sarcoma in association with invasive urothelial carcinoma involving the urinary bladder. A 67-year male patient, who presented with a complaint of macroscopic hematuria, was found to have a mass on urinary system ultrasonography. Abdominal magnetic resonance imaging was performed to evaluate the mass, which showed a 52×24 mm mass on the posterior wall of the bladder. The cystoscopic examination revealed two suspicious areas in close proximity to one another with solid-papillary character. The tissue samples were collected by means of transurethral resection. The evaluation of these samples revealed two distinct neoplastic patterns. The areas of invasive urothelial carcinoma infiltrating lamina propria were noted on the surface in addition to diffuse sheets of large cells with hyperchromatic nuclei and ample clear cytoplasm, with a patternless pattern among small lymphocytes in myxoid background in the lamina propria. The positive reactions were observed in these areas with CD45, fascin, and CD68, a histiocytic marker. The histopathological diagnosis was histiocytic sarcoma in combination with invasive urothelial carcinoma. Histiocytic sarcoma may mimic several other malignant lesions, and only immunohistochemistry can identify this tumour to allow correct treatment. We present this rare case to emphasise that this phenomenon should be considered in unusual tumors and sites. © 2022 College of Physicians and Surgeons Pakistan. All rights reserved.
dc.identifier.doi10.29271/jcpsp.2022.Supp1.S79
dc.identifier.endpageS81
dc.identifier.issn1022-386X
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85131108822
dc.identifier.scopusqualityQ3
dc.identifier.startpageS79
dc.identifier.urihttps://doi.org/10.29271/jcpsp.2022.Supp1.S79
dc.identifier.urihttps://hdl.handle.net/20.500.11776/11059
dc.identifier.volume32
dc.identifier.wosWOS:001018979100028
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorArslan, A.I.
dc.institutionauthorKarabağ, S.
dc.institutionauthorAkgül, Murat
dc.language.isoen
dc.publisherCollege of Physicians and Surgeons Pakistan
dc.relation.ispartofJournal of the College of Physicians and Surgeons Pakistan
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectHistiocytic sarcoma
dc.subjectInvasive urothelial carcinoma
dc.subjectUrinary bladder
dc.subjectCD68 antigen
dc.subjectfascin
dc.subjectreceptor type tyrosine protein phosphatase C
dc.subjectabdominal radiography
dc.subjectaged
dc.subjectArticle
dc.subjectbladder tumor
dc.subjectcancer infiltration
dc.subjectcancer staging
dc.subjectcase report
dc.subjectclinical article
dc.subjectcystoprostatectomy
dc.subjectcystoscopy
dc.subjectcytology
dc.subjectcytoplasm
dc.subjectdifferential diagnosis
dc.subjectdisease association
dc.subjectechography
dc.subjectfollow up
dc.subjecthematuria
dc.subjecthistiocytic sarcoma
dc.subjecthistopathology
dc.subjecthuman
dc.subjecthuman cell
dc.subjecthuman tissue
dc.subjectimmunohistochemistry
dc.subjectlamina propria
dc.subjectlymph node dissection
dc.subjectlymphocyte structure
dc.subjectlymphoma
dc.subjectmale
dc.subjectmelanoma
dc.subjectneuroendocrine carcinoma
dc.subjectnuclear magnetic resonance imaging
dc.subjectpostoperative period
dc.subjectprostate tissue
dc.subjecttransitional cell carcinoma
dc.subjecttransurethral resection
dc.subjecttumor invasion
dc.subjecttumor volume
dc.subjectbladder
dc.subjectbladder tumor
dc.subjectcystectomy
dc.subjectdiagnostic imaging
dc.subjectpathology
dc.subjecttransitional cell carcinoma
dc.subjectCarcinoma, Transitional Cell
dc.subjectCystectomy
dc.subjectHistiocytic Sarcoma
dc.subjectHumans
dc.subjectMale
dc.subjectUrinary Bladder
dc.subjectUrinary Bladder Neoplasms
dc.titleHistiocytic Sarcoma with Invasive Urothelial Carcinoma of Urinary Bladder
dc.typeArticle

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