Efficacy of preoperative white blood cell count and lymphocyte/monocyte ratio in predicting post-lobectomy pneumonia

dc.authorscopusid36712552600
dc.contributor.authorSarıçam, Murat
dc.date.accessioned2022-05-11T14:35:02Z
dc.date.available2022-05-11T14:35:02Z
dc.date.issued2021
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göğüs Cerrahisi Ana Bilim Dalı
dc.description.abstractBackground: This study aims to examine preoperative white blood cell count and lymphocyte/monocyte ratio and to investigate foreknown risk factors for pneumonia following lobectomy. Methods: Between January 2005 and May 2018, a total of 152 patients (135 males, 17 females; mean age: 61.9 +/- 7.5 years; range, 45 to 73 years) who underwent right lower lobectomy for non-small cell lung cancer were retrospectively analyzed. Data including age, sex, preoperative white blood cell count and lymphocyte/monocyte ratio, smoking, preexisting chronic diseases, body mass index, stage of lung cancer, the use of neoadjuvant chemotherapy, type of surgery, operation duration, blood transfusion, and postoperative intensive care unit admission were recorded. Results: Twenty-five (16.4%) patients developed postoperative pneumonia. Older patients presenting with elevated levels of preoperative white blood cell count and lymphocyte/monocyte ratio, excessive tobacco consumption, prolonged operation duration, history of a chronic disease, a body mass index over 30 kg/m(2), advanced lung cancer, neoadjuvant chemotherapy, and intensive care unit admission after surgery were at high risk for postoperative pneumonia. There was no significant difference in sex, type of surgery (thoracotomy versus thoracoscopy), and the use of blood products. In predicting the development of postoperative pneumonia, lymphocyte/monocyte ratio had 85.% sensitivity and 87.5% specificity, while white blood cell count had 72.5% sensitivity and 77.5% specificity. Conclusion: Preoperative white blood cell count and lymphocyte/monocyte ratio provide supporting evidence in predicting pneumonia following lobectomy contributing to the existing risk identification criteria.
dc.identifier.doi10.5606/tgkdc.dergisi.2021.19950
dc.identifier.endpage92
dc.identifier.issn1301-5680
dc.identifier.issue1en_US
dc.identifier.pmid33768985
dc.identifier.scopus2-s2.0-85101400445
dc.identifier.scopusqualityQ3
dc.identifier.startpage85
dc.identifier.trdizinid509424
dc.identifier.urihttps://doi.org/10.5606/tgkdc.dergisi.2021.19950
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8180
dc.identifier.volume29
dc.identifier.wosWOS:000612350500012
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.institutionauthorSarıçam, Murat
dc.language.isoen
dc.publisherBaycinar Medical Publ-Baycinar Tibbi Yayincilik
dc.relation.ispartofTurk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectLung cancer
dc.subjectlymphocyte
dc.subjectmonocyte
dc.subjectpneumonia
dc.subjectpostoperative complications
dc.subjectPostoperative Pulmonary Complications
dc.subjectThoracic-Surgery Lobectomy
dc.subjectShort-Term Outcomes
dc.subjectRisk-Factors
dc.titleEfficacy of preoperative white blood cell count and lymphocyte/monocyte ratio in predicting post-lobectomy pneumonia
dc.typeArticle

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