Investigation of Electroconvulsive Therapy Parameters in Propofol and Ketamine–Propofol Combination Anesthesia

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dc.contributor.authorBeyazyüz, Elmas
dc.contributor.authorBuse Codal, Elif
dc.contributor.authorGültekin, Ahmet
dc.contributor.authorYıldırım, İlker
dc.contributor.authorBeyazyüz, Murat
dc.date.accessioned2024-10-29T17:43:40Z
dc.date.available2024-10-29T17:43:40Z
dc.date.issued2023
dc.departmentTekirdağ Namık Kemal Üniversitesi
dc.description.abstractObjective: It is aimed to highlight the concept of electrical stimulus [electroconvulsive therapy (ECT) dose], an aspect that has not received sufficient attention in previous research on ECT. Methods: This study is a retrospective investigation aiming to examine the medical records of patients who received ECT. Patients were assigned to 2 groups. The first group received a dose of 1mg/kg propofol for ECT anesthesia (n = 25), while the second group receives a combination of 0.5 mg/kg propofol and 0.5 mg/kg ketamine (n = 36).The electrical charge required to induce an effective seizure and the parameters determining the electrical charge, such as pulse width, frequency, stimulus duration, and current, were recorded at each session and compared. Results: In propofol group the initial value of frequency was 29.03 ± 7.35 Hz and the last value (frequence at eighth session) was 83.06 ± 24.45 Hz. The difference in frequency was found to be significantly increased in propofol group (F = 151.95; ?p2 = 0.83; P < .0001). In propofol + ketamine group the initial value of frequency was 24.09 ± 7.42 Hz and the last value (frequence at eighth session) was 91.74 ± 22.39 Hz. The difference in frequency was found to be significantly increased in propofol group (F = 237.05; ?p2 = 0.95; P < .0001). The duration of session was significantly decreased in propofol group (F = 10.29; ?p2 = 0.28; P < .0001). The duration of the seizure in first session was 57.17 ± 19.09 seconds and the duration of seizure in eighth session was 50.78 ± 14.21 seconds in propofol + ketamine group. The duration of the session was significantly decreased in propofol + ketamine group. Conclusion: It was observed that the ECT dose remained similar between the 2 groups. Further research is warranted to delve into the cognitive effects of the propofol + ketamine combination in ECT procedures. © @Author(s).
dc.identifier.doi10.5152/NeuropsychiatricInvest.2023.23013
dc.identifier.endpage79
dc.identifier.issn2792-0070
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85173925907
dc.identifier.scopusqualityQ4
dc.identifier.startpage75
dc.identifier.trdizinid1263608
dc.identifier.urihttps://doi.org/10.5152/NeuropsychiatricInvest.2023.23013
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1263608
dc.identifier.urihttps://hdl.handle.net/20.500.11776/12557
dc.identifier.volume61
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherIstanbul Universitesi
dc.relation.ispartofNeuropsychiatric Investigation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCognitive
dc.subjectdepression
dc.subjectdose
dc.subjectECT
dc.subjectfrequency
dc.titleInvestigation of Electroconvulsive Therapy Parameters in Propofol and Ketamine–Propofol Combination Anesthesia
dc.title.alternativeNvestigation of Electroconvulsive Therapy Parameters in Propofol and Ketamine–Propofol Combination Anesthesia
dc.typeArticle

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