Antioxidant and anti-inflammatory activities of a commercial noni juice revealed by carrageenan-induced paw edema

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dc.authorid0000-0002-7359-6568
dc.authorid0000-0002-1589-9229
dc.authorwosidArmutak, Elif/D-2901-2019
dc.authorwosidYaylim, Ilhan/AAB-1154-2020
dc.authorwosidGurevin, Ebru Gurel/AAC-7921-2020
dc.authorwosidYAYLIM, ILHAN/AAA-9573-2021
dc.contributor.authorYılmazer, Nadim
dc.contributor.authorCoşkun, Cihan
dc.contributor.authorGürel Gürevin, Ebru
dc.contributor.authorYaylım, İlhan
dc.contributor.authorEraltan, Ethem Hakan
dc.contributor.authorİkitimur Armutak, Elif İlkay
dc.date.accessioned2022-05-11T14:28:33Z
dc.date.available2022-05-11T14:28:33Z
dc.date.issued2016
dc.departmentFakülteler, Fen Edebiyat Fakültesi, Biyoloji Bölümü
dc.description.abstractThis study aimed to investigate antioxidant and anti-inflammatory activities of a commercial product of noni (Morinda citrifolia) juice. Carrageenan-induced rat paw edema was employed as inflammatory model. One control and three experimental groups were formed. Experimental groups were administered noni juice alone, noni juice+carrageenan, and carrageenan alone. Oxidant and antioxidant capacity were determined by d-ROMs test and BAP test, respectively. Plasma concentrations of endothelin-1 and leptin were measured by ELISA. Measurements were performed at zero time and 2nd hour of inflammation. Oxidant capacity decreased in noni-received groups at 2nd hour (p=0.019). Antioxidant capacity of the group which received noni alone was found to be higher at 2nd hour (p=0.036). Plasma concentrations of endothelin-1 and leptin were notably lower in noni-received groups (p=0.001 and p=0.021, respectively). The results show that the commercial noni juice investigated has pronounced antioxidant and anti-inflammatory activities.
dc.identifier.doi10.1515/pjvs-2016-0074
dc.identifier.endpage595
dc.identifier.issn1505-1773
dc.identifier.issn2300-2557
dc.identifier.issue3en_US
dc.identifier.pmid27760029
dc.identifier.startpage589
dc.identifier.urihttps://doi.org/10.1515/pjvs-2016-0074
dc.identifier.urihttps://hdl.handle.net/20.500.11776/6868
dc.identifier.volume19
dc.identifier.wosWOS:000383528400018
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.institutionauthorYılmazer, Nadim
dc.language.isoen
dc.publisherPolska Akad Nauk, Polish Acad Sciences, Univ Warmia & Mazury Olsztyn
dc.relation.ispartofPolish Journal of Veterinary Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectcarrageenan
dc.subjectnoni (Morinda citrifolia)
dc.subjectanti-inflammatory
dc.subjectantioxidant
dc.subjectMorinda-Citrifolia L.
dc.subjectChemical-Constituents
dc.subjectOxidative Stress
dc.subjectPlasma
dc.subjectFruit
dc.subjectInflammation
dc.subjectExtract
dc.subjectDogs
dc.titleAntioxidant and anti-inflammatory activities of a commercial noni juice revealed by carrageenan-induced paw edema
dc.typeArticle

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