Antioxidant and anti-inflammatory activities of a commercial noni juice revealed by carrageenan-induced paw edema
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Date
2016
Journal Title
Journal ISSN
Volume Title
Publisher
Polska Akad Nauk, Polish Acad Sciences, Univ Warmia & Mazury Olsztyn
Access Rights
info:eu-repo/semantics/openAccess
Abstract
This study aimed to investigate antioxidant and anti-inflammatory activities of a commercial product of noni (Morinda citrifolia) juice. Carrageenan-induced rat paw edema was employed as inflammatory model. One control and three experimental groups were formed. Experimental groups were administered noni juice alone, noni juice+carrageenan, and carrageenan alone. Oxidant and antioxidant capacity were determined by d-ROMs test and BAP test, respectively. Plasma concentrations of endothelin-1 and leptin were measured by ELISA. Measurements were performed at zero time and 2nd hour of inflammation. Oxidant capacity decreased in noni-received groups at 2nd hour (p=0.019). Antioxidant capacity of the group which received noni alone was found to be higher at 2nd hour (p=0.036). Plasma concentrations of endothelin-1 and leptin were notably lower in noni-received groups (p=0.001 and p=0.021, respectively). The results show that the commercial noni juice investigated has pronounced antioxidant and anti-inflammatory activities.
Description
Keywords
carrageenan, noni (Morinda citrifolia), anti-inflammatory, antioxidant, Morinda-Citrifolia L., Chemical-Constituents, Oxidative Stress, Plasma, Fruit, Inflammation, Extract, Dogs
Journal or Series
Polish Journal of Veterinary Sciences
WoS Q Value
Q3
Scopus Q Value
Volume
19
Issue
3
