Antioxidant and anti-inflammatory activities of a commercial noni juice revealed by carrageenan-induced paw edema

Yükleniyor...
Küçük Resim

Tarih

2016

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Polska Akad Nauk, Polish Acad Sciences, Univ Warmia & Mazury Olsztyn

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

This study aimed to investigate antioxidant and anti-inflammatory activities of a commercial product of noni (Morinda citrifolia) juice. Carrageenan-induced rat paw edema was employed as inflammatory model. One control and three experimental groups were formed. Experimental groups were administered noni juice alone, noni juice+carrageenan, and carrageenan alone. Oxidant and antioxidant capacity were determined by d-ROMs test and BAP test, respectively. Plasma concentrations of endothelin-1 and leptin were measured by ELISA. Measurements were performed at zero time and 2nd hour of inflammation. Oxidant capacity decreased in noni-received groups at 2nd hour (p=0.019). Antioxidant capacity of the group which received noni alone was found to be higher at 2nd hour (p=0.036). Plasma concentrations of endothelin-1 and leptin were notably lower in noni-received groups (p=0.001 and p=0.021, respectively). The results show that the commercial noni juice investigated has pronounced antioxidant and anti-inflammatory activities.

Açıklama

Anahtar Kelimeler

carrageenan, noni (Morinda citrifolia), anti-inflammatory, antioxidant, Morinda-Citrifolia L., Chemical-Constituents, Oxidative Stress, Plasma, Fruit, Inflammation, Extract, Dogs

Kaynak

Polish Journal of Veterinary Sciences

WoS Q Değeri

Q3

Scopus Q Değeri

Cilt

19

Sayı

3

Künye