A post-treatment evaluation of total IgE, CRP and blood count parameters of children with asthma

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dc.authorscopusid8514414100
dc.authorscopusid36866111300
dc.authorscopusid6601976056
dc.authorscopusid36165893600
dc.authorscopusid37058172000
dc.authorscopusid25625782200
dc.contributor.authorTülübaş, Feti
dc.contributor.authorGürel, Ahmet
dc.contributor.authorDonma, Mustafa Metin
dc.contributor.authorNalbanto?lu, Burçin
dc.contributor.authorTopçu, Birol
dc.contributor.authorYıldız, Zeynep Deniz
dc.date.accessioned2022-05-11T14:09:56Z
dc.date.available2022-05-11T14:09:56Z
dc.date.issued2013
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Biyoistatistik Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.description.abstractObjective: We aimed to study if inhaled corticosteroid and inhaled beta 2 agonist treatment to 2-18 years old children with asthma resulted in recovery in serum total IgE, CRP, and whole blood count levels and/or to evaluate the effect of treatment in comparison to healthy children. Methods: Data regarding pre and post treatment serum total IgE, CRP, and hemogram levels of 2-18 years old, 99 children with asthma, who received inhaled corticosteroid and inhaled beta 2 agonist treatment and who applied to Nami{dotless}k Kemal University Research and Practice Hospital Pediatrics Clinic, were obtained through file scanning. Data regarding demographics and serum total IgE, CRP and hemogram levels of 99 healthy children in control group were also obtained through file scanning. Results: In children with asthma, levels of serum total IgE, lymphocyte, eosinophil and basophil counts and percentages were significantly increased compared to healthy controls, and they were significantly decreased after treatment to the levels of healthy controls. Serum CRP levels, neutrophil counts and percentages were significantly decreased compared to healthy controls, and they were significantly increased after treatment. Conclusions: Inhaled steroid and beta 2 antagonist treatment to children with asthma resulted in recovery in levels of IgE, CRP, and some whole blood count parameters through decreasing inflammation with its anti-inflammatory effect.
dc.identifier.endpage10
dc.identifier.issn1307-671X
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84888088034
dc.identifier.scopusqualityQ4
dc.identifier.startpage7
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5212
dc.identifier.volume15
dc.indekslendigikaynakScopus
dc.institutionauthorTülübaş, Feti
dc.institutionauthorGürel, Ahmet
dc.institutionauthorDonma, Mustafa Metin
dc.institutionauthorNalbanto?lu, Burçin
dc.institutionauthorTopçu, Birol
dc.institutionauthorYıldız, Zeynep Deniz
dc.language.isoen
dc.relation.ispartofDuzce Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAsthma
dc.subjectCRP
dc.subjectHemogram
dc.subjectIgE
dc.subjectbeta 2 adrenergic receptor stimulating agent
dc.subjectC reactive protein
dc.subjectcorticosteroid
dc.subjectimmunoglobulin E
dc.subjectadolescent
dc.subjectadult
dc.subjectantiinflammatory activity
dc.subjectarticle
dc.subjectasthma
dc.subjectbasophil
dc.subjectblood cell count
dc.subjectchild
dc.subjectcontrolled study
dc.subjectdemography
dc.subjectdrug response
dc.subjecteosinophil count
dc.subjecthuman
dc.subjectimmunoglobulin blood level
dc.subjectinflammation
dc.subjectleukocyte count
dc.subjectlymphocyte count
dc.subjectmajor clinical study
dc.subjectneutrophil count
dc.subjectpreschool child
dc.subjectprotein blood level
dc.subjectschool child
dc.titleA post-treatment evaluation of total IgE, CRP and blood count parameters of children with asthma
dc.title.alternativeAsti{dotless}mli{dotless} çocuklarda tedavi sonrasi{dotless} total IgE, CRP ve tam kan sayi{dotless}m parametrelerinin de?erlendirilmesi]
dc.typeArticle

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