A post-treatment evaluation of total IgE, CRP and blood count parameters of children with asthma
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Dosyalar
Tarih
2013
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: We aimed to study if inhaled corticosteroid and inhaled beta 2 agonist treatment to 2-18 years old children with asthma resulted in recovery in serum total IgE, CRP, and whole blood count levels and/or to evaluate the effect of treatment in comparison to healthy children. Methods: Data regarding pre and post treatment serum total IgE, CRP, and hemogram levels of 2-18 years old, 99 children with asthma, who received inhaled corticosteroid and inhaled beta 2 agonist treatment and who applied to Nami{dotless}k Kemal University Research and Practice Hospital Pediatrics Clinic, were obtained through file scanning. Data regarding demographics and serum total IgE, CRP and hemogram levels of 99 healthy children in control group were also obtained through file scanning. Results: In children with asthma, levels of serum total IgE, lymphocyte, eosinophil and basophil counts and percentages were significantly increased compared to healthy controls, and they were significantly decreased after treatment to the levels of healthy controls. Serum CRP levels, neutrophil counts and percentages were significantly decreased compared to healthy controls, and they were significantly increased after treatment. Conclusions: Inhaled steroid and beta 2 antagonist treatment to children with asthma resulted in recovery in levels of IgE, CRP, and some whole blood count parameters through decreasing inflammation with its anti-inflammatory effect.
Açıklama
Anahtar Kelimeler
Asthma, CRP, Hemogram, IgE, beta 2 adrenergic receptor stimulating agent, C reactive protein, corticosteroid, immunoglobulin E, adolescent, adult, antiinflammatory activity, article, asthma, basophil, blood cell count, child, controlled study, demography, drug response, eosinophil count, human, immunoglobulin blood level, inflammation, leukocyte count, lymphocyte count, major clinical study, neutrophil count, preschool child, protein blood level, school child
Kaynak
Duzce Medical Journal
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
15
Sayı
1
