Structural and biological features of bismuth(III) halide complexes with heterocyclic thioamides
Yükleniyor...
Dosyalar
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier B.V.
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Ten novel bismuth(III) halide complexes of [Bi(L)X3]n, [Bi(L)2×3]2, and [Bi(L)3×3] structural types were synthesized, in which L: 5-ethoxy-2-mercaptobenzimidazole, 5?methoxy-2-mercaptobenzimidazole and N-methylbenzothiazole. Bismuth(III) halide complexes 1–10 were characterized by melting point, elemental analysis, molar conductivity, FT-IR, FT-Raman, UV-Visible, 1H and 13C NMR spectroscopic techniques, as well as by the Thermogravimetric-Differential Thermal Analysis (TG-DTA). The crystal structures of complexes 1–10 were determined by using single crystal X-ray diffraction study. The results show that the bismuth(III) complexes exist as monomer (4), doubly-bridged dimer (1–3 and 5–9), and edge-sharing polymer (10), in which the central bismuth atom is a six-coordinated and adopts distorted octahedral geometries. We report here, for the first time, cis-sulfur, cis-halide arrangement of the doubly-bridged dimer bismuth(III) complexes. The intermolecular interactions in bismuth(III) complexes play a very important role in the supramolecular architecture. A detailed analysis of the intermolecular interactions has been performed as based on the Hirshfeld surfaces and their associated two-dimensional fingerprint plots. Bismuth(III) halide complexes 1–10 and their free ligands have been screened for antimicrobial activity against two Gram negative bacteria (Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853) and two Gram positive bacteria (Staphylococcus aureus ATCC 25923 and Enterococcus faecalis ATCC 29212). The influence of complexes 1–10 and the free ligands on the catalytic peroxidation of the linoleic acid by the enzyme lipoxygenase (LOX) has been determined experimentally and theoretically. © 2020
Açıklama
Anahtar Kelimeler
Antibacterial activity, Bismuth (III) halides, Hirshfeld surface analysis, Lipoxygenase, Thioamides, Bismuth metallography, Complexation, Differential thermal analysis, Dimers, Escherichia coli, Ligands, Linoleic acid, Metal halides, Single crystals, Spectroscopic analysis, Synthesis (chemical), Thermogravimetric analysis, Anti-microbial activity, Gram-positive bacterium, Intermolecular interactions, Single-crystal X-ray diffraction studies, Spectroscopic technique, Supramolecular architectures, Thermogravimetric-differential thermal analysis, Two-dimensional fingerprint, Bismuth compounds
Kaynak
Journal of Molecular Structure
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
1227
