Why Crossmatch Tests are Very Important and What Do They Tell Us?

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dc.authorscopusid8624948000
dc.authorscopusid9242258800
dc.contributor.authorTitiz, Mesut İzzet
dc.contributor.authorBilgen, Türker
dc.date.accessioned2022-05-11T14:02:58Z
dc.date.available2022-05-11T14:02:58Z
dc.date.issued2020
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı
dc.departmentRektörlüğe Bağlı Bölümler, Rektörlük, Bilimsel ve Teknolojik Araştırmalar Uygulama ve Araştırma Merkezi
dc.description.abstractOrgan transplantation is a very complex procedure that can save lives. It is a very useful procedure if the concepts of immunology, gained through bitter experience over the years, are kept in mind during practice. Allogeneic sensitization due to previous exposure(s) to alloantigens can hamper the procedure and remains the main obstacle to organ transplantation. Allosensitization and its level in a patient can be revealed before transplantation using the crossmatch test performed by incubating the patient’s serum with the possible donor’s lymphocytes in a laboratory environment. Crossmatch tests are routinely used prior to transplantation to prevent acute humoral reactions to the allograft tissue following reperfusion and also for long-term monitoring of the patient’s humoral status during the pre- and post-transplantation periods. © 2020 Turkish Society of Nephrology. All rights reserved.
dc.identifier.doi10.5152/turkjnephrol.2020.3900
dc.identifier.endpage81
dc.identifier.issn2667-4440
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85087987403
dc.identifier.scopusqualityQ4
dc.identifier.startpage17
dc.identifier.urihttps://doi.org/10.5152/turkjnephrol.2020.3900
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4559
dc.identifier.volume29
dc.identifier.wosWOS:000514116300013
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorTitiz, Mesut İzzet
dc.institutionauthorBilgen, Türker
dc.language.isoen
dc.publisherTurkish Society of Nephrology
dc.relation.ispartofTurkish Journal of Nephrology
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCrossmatch test
dc.subjectSensitization
dc.subjectTransplantation
dc.titleWhy Crossmatch Tests are Very Important and What Do They Tell Us?
dc.title.alternativeWhy crossmatch tests are very important and what do they tell us?
dc.typeReview Article

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