Pathological Yawning in Patients with Acute Middle Cerebral Artery Infarction: Prognostic Significance and Association with the Infarct Location

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Küçük Resim

Tarih

2020

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Galenos Publishing House

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Background: Pathological yawning is a compulsive, frequent, repetitive yawning triggered by a specific reason besides fatigue or boredom. It may be related to iatrogenic, neurologic, psychiatric, gastrointestinal, or metabolic disorders. Moreover, it could also be seen in the course of an ischemic stroke. Aims: To determine whether pathological yawning is a prognostic marker of middle cerebral artery stroke and evaluate its relationship with the infarct location. Study Design: Cross-sectional study. Methods: We examined 161 patients with acute middle cerebral artery stroke, consecutively admitted to emergency department. Demographic information, stroke risk factors, stroke type according to Trial of Org 10172 in Acute Stroke Treatment classification, blood oxygen saturation, body temperature, blood pressure, heart rate, glucose levels, daytime of stroke onset, National Institutes of Health Stroke Scale score (National Institutes of Health Stroke Scale score, at admission and 24 h), modified Rankin scale (at 3 months), and infarct locations were documented. Pathological yawning was defined as ?3 yawns/15 min. All patients were observed for 6 hours to detect pathological yawning. National Institutes of Health Stroke Scale score >10 was determined as severe stroke. The correlation between the presence of pathological yawning and stroke severity, infarct location, and the short-and long-term outcomes of the patients were evaluated. Results: Sixty-nine (42.9%) patients had pathological yawning and 112 (69.6%) had cortical infarcts. Insular and opercular infarcts were detected in 65 (40.4%) and 54 (33.5%) patients, respectively. Pathological yawning was more frequently observed in patients with cortical, insular, and opercular infarcts (p<0.05). Pathological yawning was related to higher National Institutes of Health Stroke Scale scores. Patients with severe stroke (National Institutes of Health Stroke Scale score ?10) presented with more pathological yawning than those with mild to moderate strokes (p<0.05). The clinical outcomes and mortality rates showed no significant relationship with the occurrence of pathological yawning. Conclusion: Pathological yawning in middle cerebral artery stroke was associated with stroke severity, presence of cortical involvement, and insular and opercular infarcts. However, no association was found with long-term outcome and mortality. ©Copyright 2020 by Trakya University Faculty of Medicine / The Balkan Medical Journal published by Galenos Publishing House.

Açıklama

Anahtar Kelimeler

Anterior cerebral circulation, Infarct location, Middle cerebral artery infarction, Pathological yawning, Prognosis, glucose, adult, aged, Article, atrial fibrillation, blood oxygen tension, blood pressure, body temperature, cerebral artery disease, clinical outcome, cohort analysis, controlled study, coronary artery disease, cross-sectional study, demography, diabetes mellitus, disease activity, disease association, disease classification, disease duration, disease severity, emergency ward, female, glucose level, heart failure, heart rate, hospital admission, human, hyperlipidemia, hypertension, infarct volume, major clinical study, male, metabolic syndrome X, mortality rate, National Institutes of Health Stroke Scale, observational study, outcome assessment, prognosis, prognostic assessment, Rankin scale, risk factor, tobacco use, transient ischemic attack, treatment duration, yawning, adolescent, cerebral artery disease, cerebrovascular accident, chi square distribution, classification, middle aged, nonparametric test, pathophysiology, physiology, severity of illness index, very elderly, yawning, Adolescent, Adult, Aged, Aged, 80 and over, Chi-Square Distribution, Cross-Sectional Studies, Female, Humans, Infarction, Middle Cerebral Artery, Male, Middle Aged, Prognosis, Severity of Illness Index, Statistics, Nonparametric, Stroke, Yawning

Kaynak

Balkan Medical Journal

WoS Q Değeri

Q3

Scopus Q Değeri

Q3

Cilt

37

Sayı

1

Künye