The Safe Surgical Margin for the Testis Sparing Surgery in Testicular Cancer

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dc.contributor.authorAkgul, M.
dc.contributor.authorArslan, A., I
dc.contributor.authorYazici, C. M.
dc.date.accessioned2024-10-29T17:59:31Z
dc.date.available2024-10-29T17:59:31Z
dc.date.issued2023
dc.departmentTekirdağ Namık Kemal Üniversitesi
dc.description.abstractBackground: Testis sparing surgery (TSS) has an important role in preserving the functional capacity of testicular cancer (TC). Germ cell neoplasia in situ (GCNIS) lesions in the remaining testis have a significant risk for local recurrence. Aim: We aimed to evaluate the presence of satellite GCNIS lesions around the primary tumor and to measure the distance of the furthest GCNIS lesion to the primary tumor. Subject and Methods: The radical orchiectomy specimens of patients (n = 37) with a tumor size of <= 3 cm were reevaluated by the same pathologist. The satellite GCNIS lesions located around the primary tumor were detected, and the furthest GCNIS lesion distance to the primary tumor was measured under light microscopy. Results: The mean tumor size was 1,9 +/- 0,6 cm. The mean furthest GCNIS distance to the primary tumor was 5,08 +/- 2,77 mm. A total of 19 (51,4%) patients had the furthest GCNIS lesions <5 mm, and 28 (75,6%) patients had the furthest GCNIS lesions <7 mm away from the primary lesion. Conclusions: Leaving a 5 mm safety margin during TSS would lead to excise the satellite GCNIS lesions in half of the patients. Increasing the safety margin to 7 mm would lead to excise the satellite GCNIS lesions at 75% of the patients.
dc.identifier.doi10.4103/njcp.njcp_348_23
dc.identifier.endpage1733
dc.identifier.issn1119-3077
dc.identifier.issn2229-7731
dc.identifier.issue11en_US
dc.identifier.pmid38044780
dc.identifier.scopus2-s2.0-85178651734
dc.identifier.scopusqualityQ3
dc.identifier.startpage1728
dc.identifier.urihttps://doi.org/10.4103/njcp.njcp_348_23
dc.identifier.urihttps://hdl.handle.net/20.500.11776/14761
dc.identifier.volume26
dc.identifier.wosWOS:001114512300013
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWolters Kluwer Medknow Publications
dc.relation.ispartofNigerian Journal of Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectGerm cell neoplasia in situ
dc.subjectradical orchiectomy
dc.subjectsurgical margin
dc.subjecttesticular cancer
dc.subjecttestis sparing surgery
dc.titleThe Safe Surgical Margin for the Testis Sparing Surgery in Testicular Cancer
dc.typeArticle

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