The Safe Surgical Margin for the Testis Sparing Surgery in Testicular Cancer

Küçük Resim Yok

Tarih

2023

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Wolters Kluwer Medknow Publications

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Background: Testis sparing surgery (TSS) has an important role in preserving the functional capacity of testicular cancer (TC). Germ cell neoplasia in situ (GCNIS) lesions in the remaining testis have a significant risk for local recurrence. Aim: We aimed to evaluate the presence of satellite GCNIS lesions around the primary tumor and to measure the distance of the furthest GCNIS lesion to the primary tumor. Subject and Methods: The radical orchiectomy specimens of patients (n = 37) with a tumor size of <= 3 cm were reevaluated by the same pathologist. The satellite GCNIS lesions located around the primary tumor were detected, and the furthest GCNIS lesion distance to the primary tumor was measured under light microscopy. Results: The mean tumor size was 1,9 +/- 0,6 cm. The mean furthest GCNIS distance to the primary tumor was 5,08 +/- 2,77 mm. A total of 19 (51,4%) patients had the furthest GCNIS lesions <5 mm, and 28 (75,6%) patients had the furthest GCNIS lesions <7 mm away from the primary lesion. Conclusions: Leaving a 5 mm safety margin during TSS would lead to excise the satellite GCNIS lesions in half of the patients. Increasing the safety margin to 7 mm would lead to excise the satellite GCNIS lesions at 75% of the patients.

Açıklama

Anahtar Kelimeler

Germ cell neoplasia in situ, radical orchiectomy, surgical margin, testicular cancer, testis sparing surgery

Kaynak

Nigerian Journal of Clinical Practice

WoS Q Değeri

Q3

Scopus Q Değeri

Q3

Cilt

26

Sayı

11

Künye