The Safe Surgical Margin for the Testis Sparing Surgery in Testicular Cancer
Küçük Resim Yok
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wolters Kluwer Medknow Publications
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: Testis sparing surgery (TSS) has an important role in preserving the functional capacity of testicular cancer (TC). Germ cell neoplasia in situ (GCNIS) lesions in the remaining testis have a significant risk for local recurrence. Aim: We aimed to evaluate the presence of satellite GCNIS lesions around the primary tumor and to measure the distance of the furthest GCNIS lesion to the primary tumor. Subject and Methods: The radical orchiectomy specimens of patients (n = 37) with a tumor size of <= 3 cm were reevaluated by the same pathologist. The satellite GCNIS lesions located around the primary tumor were detected, and the furthest GCNIS lesion distance to the primary tumor was measured under light microscopy. Results: The mean tumor size was 1,9 +/- 0,6 cm. The mean furthest GCNIS distance to the primary tumor was 5,08 +/- 2,77 mm. A total of 19 (51,4%) patients had the furthest GCNIS lesions <5 mm, and 28 (75,6%) patients had the furthest GCNIS lesions <7 mm away from the primary lesion. Conclusions: Leaving a 5 mm safety margin during TSS would lead to excise the satellite GCNIS lesions in half of the patients. Increasing the safety margin to 7 mm would lead to excise the satellite GCNIS lesions at 75% of the patients.
Açıklama
Anahtar Kelimeler
Germ cell neoplasia in situ, radical orchiectomy, surgical margin, testicular cancer, testis sparing surgery
Kaynak
Nigerian Journal of Clinical Practice
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
26
Sayı
11