Survey and Characterization of Jingmen Tick Virus Variants

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dc.authorid0000-0001-5422-1982
dc.authorid0000-0001-5008-9443
dc.authorid0000-0001-8185-3176
dc.authorid0000-0002-5493-0807
dc.authorscopusid26326680200
dc.authorscopusid52263886700
dc.authorscopusid15769247000
dc.authorscopusid57209228994
dc.authorscopusid55258915300
dc.authorscopusid7004626809
dc.authorscopusid7004873534
dc.authorwosidLinton, Yvonne-Marie/AAW-3992-2021
dc.authorwosidhacioglu, sabri/ABG-9827-2021
dc.authorwosidOzkul, Aykut/A-1973-2016
dc.authorwosidErgunay, Koray/I-8368-2013
dc.contributor.authorDinçer, Ender
dc.contributor.authorHacioglu, Sabri
dc.contributor.authorKar, Sırrı
dc.contributor.authorEmanet, Nergis
dc.contributor.authorBrinkmann, Annika
dc.contributor.authorNitsche, Andreas
dc.contributor.authorErgünay, Koray
dc.date.accessioned2022-05-11T14:28:40Z
dc.date.available2022-05-11T14:28:40Z
dc.date.issued2019
dc.departmentFakülteler, Fen Edebiyat Fakültesi, Biyoloji Bölümü
dc.description.abstractWe obtained a Jingmen tick virus (JMTV) isolate, following inoculation of a tick pool with detectable Crimean-Congo hemorrhagic fever virus (CCHFV) RNA. We subsequently screened 7223 ticks, representing 15 species in five genera, collected from various regions in Anatolia and eastern Thrace, Turkey. Moreover, we tested specimens from various patient cohorts (n = 103), and canine (n = 60), bovine (n = 20) and avian specimens (n = 65). JMTV nucleic acids were detected in 3.9% of the tick pools, including those from several tick species from the genera Rhipicephalus and Haemaphysalis, and Hyalomma marginatum, the main vector of CCHFV in Turkey. Phylogenetic analysis supported two separate clades, independent of host or location, suggesting ubiquitous distribution in ticks. JMTV was not recovered from any human, animal or bird specimens tested. Near-complete viral genomes were sequenced from the prototype isolate and from three infected tick pools. Genome topology and functional organization were identical to the members of Jingmen group viruses. Phylogenetic reconstruction of individual viral genome segments and functional elements further supported the close relationship of the strains from Kosovo. We further identified probable recombination events in the JMTV genome, involving closely-related strains from Anatolia or China.
dc.description.sponsorshipArmed Forces Health Surveillance Board, Global Emerging Infections Surveillance and Response System (AFHSB-GEIS), United States of America under US Army [FY18, P0034_18_WR, W911QY-16-C-0160]
dc.description.sponsorshipThe study was supported in part by the Armed Forces Health Surveillance Board, Global Emerging Infections Surveillance and Response System (AFHSB-GEIS), United States of America (FY18 award P0034_18_WR (PI: Yvonne-Marie Linton) under US Army subcontract W911QY-16-C-0160).
dc.identifier.doi10.3390/v11111071
dc.identifier.issn1999-4915
dc.identifier.issue11en_US
dc.identifier.pmid31744216
dc.identifier.scopus2-s2.0-85075304817
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3390/v11111071
dc.identifier.urihttps://hdl.handle.net/20.500.11776/6907
dc.identifier.volume11
dc.identifier.wosWOS:000502292300099
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKar, Sırrı
dc.language.isoen
dc.publisherMdpi
dc.relation.ispartofViruses-Basel
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectjingmen
dc.subjecttick
dc.subjectflavivirus
dc.subjectAnatolia
dc.subjectturkey
dc.subjectNs5 Protein
dc.subjectIdentification
dc.subjectFlaviviruses
dc.subjectEpidemiology
dc.subjectDiversity
dc.subjectEmergence
dc.subjectAlignment
dc.subjectDomain
dc.subjectAcari
dc.titleSurvey and Characterization of Jingmen Tick Virus Variants
dc.typeArticle

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