SYNTHESIS, CHARACTERIZATION AND HIRSHFELD SURFACE ANALYSIS OF SOME THIOSEMICARBAZONES CONTAINING A FIVE-MEMBERED RING

Küçük Resim Yok

Tarih

2023

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Pleiades Publishing Inc

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Thiosemicarbazones, which are multidentate ligands, are considered as one of the most important classes of organic compounds due to their broad spectrum of pharmacological effects and their ability to coordinate easily with metal ions. Four thiosemicarbazones, furan-2-carbaldehyde-N-methyl thiosemicarbazone (Hfmtsc), thiophene-2-acetaldehyde thiosemicarbazone (Hattsc), thiophene-2-acetaldehyde-N-methyl thiosemicarbazone (Hatmtsc) and thiophene-2-acetaldehyde-N-ethyl thiosemicarbazone (Hatetsc) were successfully prepared via condensation reaction using substituted aldehyde and (un)substituted thiosemicarbazides. They were characterized by melting point, elemental analysis, molar conductivity, FTIR, UV-Vis, H-1 and C-13 NMR spectroscopic techniques. The crystal structure of them was determined by using single crystal X-ray diffraction study. Intermolecular interactions were investigated by Hirshfeld surface analysis. Molecular structure of compounds was stabilized by N-H center dot center dot center dot S, C-H center dot center dot center dot S, N-H center dot center dot center dot O and C-H center dot center dot center dot O interactions. In each compound, the molecules are connected into R-2(2)(8) dimers via pairs of N-H center dot center dot center dot S interactions.

Açıklama

Anahtar Kelimeler

thiosemicarbazones, spectral characterization, X-ray structure analysis, Hirshfeld surface analysis

Kaynak

Journal of Structural Chemistry

WoS Q Değeri

Q4

Scopus Q Değeri

Q4

Cilt

64

Sayı

5

Künye