Immunohistochemical examination of effects of kefir, koumiss and commercial probiotic capsules on platelet derived growth factor-c and platelet derived growth factor receptor-alpha expression in mouse liver and kidney

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dc.authorscopusid37121662100
dc.authorscopusid26640705000
dc.authorscopusid56577807500
dc.authorscopusid55336402900
dc.authorwosidbakır, buket/ABA-8248-2020
dc.contributor.authorBakır, Buket
dc.contributor.authorSarı, Ebru Karadağ
dc.contributor.authorAydın, B. D.
dc.contributor.authorYıldız, S. E.
dc.date.accessioned2022-05-11T14:42:27Z
dc.date.available2022-05-11T14:42:27Z
dc.date.issued2015
dc.departmentFakülteler, Veteriner Fakültesi, Temel Bilimler Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalı
dc.description.abstractWe investigated using immunohistochemistry the effects of kefir, koumiss and commercial probiotic capsules on the expression of platelet derived growth factor-c (PDGF-C) and platelet derived growth factor receptor-alpha (PDGFR-alpha) in mouse liver and kidney. Mice were assigned to four groups: group 1 was given commercial probiotic capsules, group 2 was given kefir, group 3 was given koumiss and group 4 was untreated. After oral administration for 15 days, body weights were recorded and liver and kidney tissue samples were obtained. Hematoxylin and eosin staining was used to examine histology. PDGF-C and PDGFR-alpha in liver and kidney were localized using the streptavidin-biotin peroxidase complex method (ABC). We found that the weights of the mice in the kefir, koumiss and commercial probiotic capsules groups increased compared to the control group. No differences in liver and kidney histology were observed in any of the experimental groups. Kefir, koumiss and the commercial probiotic preparation increased PDGF-C and PDGFR-alpha expression.
dc.description.sponsorshipCommission for the Scientific Research Projects of Kafkas UniversityKafkas University [2012-VF-5]
dc.description.sponsorshipThis Project was supported by the Commission for the Scientific Research Projects of Kafkas University, project number 2012-VF-5.
dc.identifier.doi10.3109/10520295.2014.976841
dc.identifier.endpage196
dc.identifier.issn1052-0295
dc.identifier.issn1473-7760
dc.identifier.issue3en_US
dc.identifier.pmid25420892
dc.identifier.scopus2-s2.0-84964282511
dc.identifier.scopusqualityQ2
dc.identifier.startpage190
dc.identifier.urihttps://doi.org/10.3109/10520295.2014.976841
dc.identifier.urihttps://hdl.handle.net/20.500.11776/9380
dc.identifier.volume90
dc.identifier.wosWOS:000352110200005
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorBakır, Buket
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofBiotechnic & Histochemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectkefir
dc.subjectkidney
dc.subjectkoumiss
dc.subjectliver
dc.subjectPDGF-C
dc.subjectPDGFR-alpha
dc.subjectprobiotic
dc.subjectPdgf-C
dc.subjectMilk-Kefir
dc.titleImmunohistochemical examination of effects of kefir, koumiss and commercial probiotic capsules on platelet derived growth factor-c and platelet derived growth factor receptor-alpha expression in mouse liver and kidney
dc.typeArticle

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