Outcomes of Carotid Artery Stenting in Elderly Patients: A Single Center Retrospective Study: the Effect of Post-dilatation on Outcomes

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dc.authorscopusid16315021800
dc.authorscopusid57226870481
dc.authorscopusid55317577700
dc.authorscopusid6505680586
dc.authorscopusid7005837198
dc.contributor.authorAkyüz, Aydın
dc.contributor.authorEfe, Muhammet Mucip
dc.contributor.authorÖzkaramanlı Gür, Demet
dc.contributor.authorAlpsoy, Şeref
dc.contributor.authorGüler, Niyazi
dc.date.accessioned2022-05-11T14:40:11Z
dc.date.available2022-05-11T14:40:11Z
dc.date.issued2021
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractObjective: Carotid artery stenting (CAS) is a current treatment approach that has been applied in symptomatic and asymptomatic carotid artery stenosis. In addition to being a minimally invasive method, it has fewer complications and mortality rates, and short hospital stays when compared to carotid endarterectomy. Some studies showed that the risk of stroke or death twice as high after CAS than after carotid endarterectomy among those ?70 years old. In this study, we aimed to investigate the short- and long-term complications, efficacy, and durability of CAS in elderly patients (?70 years old) with carotid artery stenosis with a median follow-up of 5.08 years (interquartile range 3.2-8.1), respectively. Material and Methods: A total of 140 patients who underwent CAS due to atherosclerotic carotid artery stenosis were included in the study. Stroke rates (total n=15[10.7%], n=3[5%] vs n=12[15%], p=0.049) were higher in patients who were ?70 years of age during the follow-up. The two groups (the group with age <70 and the group with age ?70) were compared according to demographic, biochemical data, and clinical outcomes such as stroke and stroke/death. Results: According to multivariate logistic regression analysis, those who were ?70 years, those with a history of earlier stroke, and the patients requiring post-dilatation were at risk of recurrent stroke. Deaths occurred in 5 of 140 patients in the follow-up. The patients who were ?70 years (OR 4.577 [95% CI=1.023-5.544], p=0.043), who have a history of earlier stroke (OR=6.965 [95% CI=1.067-13.115], p=0.038), and those requiring post-dilatation (OR=2.312 [95%CI=1.156-5.775], p=0.022) were at risk of recurrent stroke. Only age ?70 years (OR=4.577 [95% CI=1.210-17.191], p=0.024) was an important risk factor for death/stroke. Conclusion: Although the immediate results of the CAS procedure in patients with age ?70, were successful, they, especially in those with a history of earlier stroke and those requiring post-dilation, had a higher risk of stroke and the combined endpoint of death/stroke in the follow-up. Copyright © 2021 by Türkiye Klinikleri.
dc.identifier.doi10.5336/cardiosci.2020-78229
dc.identifier.endpage14
dc.identifier.issn1306-7656
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85113153358
dc.identifier.scopusqualityQ4
dc.identifier.startpage7
dc.identifier.urihttps://doi.org/10.5336/cardiosci.2020-78229
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8893
dc.identifier.volume33
dc.indekslendigikaynakScopus
dc.institutionauthorAkyüz, Aydın
dc.institutionauthorEfe, Muhammet Mucip
dc.institutionauthorÖzkaramanlı Gür, Demet
dc.institutionauthorAlpsoy, Şeref
dc.institutionauthorGüler, Niyazi
dc.language.isoen
dc.publisherOrtadoğu Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S.
dc.relation.ispartofTurkiye Klinikleri Cardiovascular Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCarotid arteries
dc.subjectDeath
dc.subjectStents
dc.subjectStroke
dc.subjectacetylsalicylic acid plus clopidogrel
dc.subjectcontrast medium
dc.subjectheparin
dc.subjectadult
dc.subjectaged
dc.subjectArticle
dc.subjectballoon dilatation
dc.subjectbolus injection
dc.subjectbradycardia
dc.subjectbrain damage
dc.subjectbrain hemorrhage
dc.subjectcarotid artery obstruction
dc.subjectcarotid artery stenting
dc.subjectcarotid atherosclerosis
dc.subjectcerebral hyperperfusion syndrome
dc.subjectcerebrovascular accident
dc.subjectcerebrovascular disease
dc.subjectclinical outcome
dc.subjectcomparative study
dc.subjectcomputer assisted tomography
dc.subjectcontrolled study
dc.subjectdata analysis software
dc.subjectdemography
dc.subjectdiabetes mellitus
dc.subjectdisease severity
dc.subjectDoppler flowmetry
dc.subjectfemale
dc.subjectfollow up
dc.subjectgeriatric patient
dc.subjectheart infarction
dc.subjecthigh risk patient
dc.subjecthuman
dc.subjecthyperlipidemia
dc.subjecthypertension
dc.subjecthypotension
dc.subjectischemic heart disease
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmedical history
dc.subjectmedical record review
dc.subjectmiddle aged
dc.subjectmortality rate
dc.subjectmultivariate logistic regression analysis
dc.subjectobesity
dc.subjectrecurrent disease
dc.subjectretrospective study
dc.subjectrisk factor
dc.titleOutcomes of Carotid Artery Stenting in Elderly Patients: A Single Center Retrospective Study: the Effect of Post-dilatation on Outcomes
dc.title.alternativeYaşlı Hastalarda Karotid Arter Stent Sonuçları: Tek Merkezi Retrospektif Bir Çalışma: Post-dilatasyonun Sonuçlara Etkisi]
dc.typeArticle

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