Genetic characterization of some Turkish sheep breeds based on the sequencing of the Ovar-DRB1 gene in the major histocompatibility complex (MHC) gene region

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dc.authorid0000-0003-2982-6562
dc.authorid0000-0003-2982-6562
dc.authorid0000-0002-5298-6997
dc.authorscopusid26028615800
dc.authorscopusid36854988700
dc.authorscopusid57200696504
dc.authorwosidÖzdil, Fulya/ABA-4197-2020
dc.authorwosidIşık, Raziye/V-4030-2017
dc.authorwosidISIK, RAZIYE/O-2454-2019
dc.contributor.authorÖzdil, Fulya
dc.contributor.authorİlhan, Fatma
dc.contributor.authorIşık, Raziye
dc.date.accessioned2022-05-11T14:45:28Z
dc.date.available2022-05-11T14:45:28Z
dc.date.issued2018
dc.departmentFakülteler, Ziraat Fakültesi, Tarımsal Biyoteknoloji Bölümü
dc.description.abstractIn this research, Ovar-DRB1 gene in the major histocompatibility complex (MHC) gene region was surveyed by DNA sequencing in some of the native sheep breeds that are reared in Turkey. A total of 80 samples were collected from eight different Turkish native sheep breeds, and these samples were used for DNA sequencing. The exon 2 region of Ovar-DRB1 in the MHC gene region was polymerase chain reaction (PCR) amplified and sequenced. A total of 25 new alleles were revealed in the Ovar-DRB1 gene in Turkish native sheep breeds with 24 variable sites; only 13 sites were parsimony informative. The average pairwise genetic distance was 0.029 % for the Ovar-DRBI gene exon 2 region. The sequence variations at eight different positions (7026, 7036, 7040, 7053, 7059, 7069, 7131 and 7214) are found in all of the studied samples. G -> C transversion at position 7081 is only seen in Akkaraman sheep breed, whereas T -> C transition at position 7097 is only seen in one sample from the Akkaraman breed. Overall, two main groups were detected among the 25 alleles from Turkish native sheep breeds. All Daglic and Kivircik alleles and one allele from Karayaka, Malya and Sakiz are grouped together while all the other breeds are grouped in the other branch.
dc.description.sponsorshipSelcuk University, The Scientific Research Projects Coordinating OfficeSelcuk University [12401025]
dc.description.sponsorshipWe thank Selcuk University, The Scientific Research Projects Coordinating Office (project no: 12401025; principal investigator: Fulya Ozdil).
dc.identifier.doi10.5194/aab-61-475-2018
dc.identifier.endpage480
dc.identifier.issn0003-9438
dc.identifier.issn2363-9822
dc.identifier.issue4en_US
dc.identifier.pmid32175456
dc.identifier.scopus2-s2.0-85060777911
dc.identifier.scopusqualityQ2
dc.identifier.startpage475
dc.identifier.urihttps://doi.org/10.5194/aab-61-475-2018
dc.identifier.urihttps://hdl.handle.net/20.500.11776/10052
dc.identifier.volume61
dc.identifier.wosWOS:000452379100003
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÖzdil, Fulya
dc.institutionauthorIşık, Raziye
dc.language.isoen
dc.publisherCopernicus Gesellschaft Mbh
dc.relation.ispartofArchives Animal Breeding
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectIi Drb1 Alleles
dc.subject2nd Exon
dc.subjectPolymorphism
dc.subjectResistance
dc.subjectDna
dc.subjectDiversity
dc.titleGenetic characterization of some Turkish sheep breeds based on the sequencing of the Ovar-DRB1 gene in the major histocompatibility complex (MHC) gene region
dc.typeArticle

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