Spectrum of histopathological lesions in laparoscopic cholecystectomy specimens and incidental carcinoma rate: Our surgical and clinical experience

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dc.authorscopusid55624501100
dc.authorscopusid17433815200
dc.authorscopusid8204207500
dc.authorscopusid56414492000
dc.authorscopusid55445082300
dc.authorscopusid56387511700
dc.authorscopusid35410250800
dc.contributor.authorBali, İlhan
dc.contributor.authorEmir, Seyfi
dc.contributor.authorGürdal, S.Ö.
dc.contributor.authorTuran, Bünyamin Cüneyt
dc.contributor.authorYıldırım, Oğuzhan
dc.contributor.authorSakallı, Onur
dc.contributor.authorSözen, Selim
dc.date.accessioned2022-05-11T14:10:04Z
dc.date.available2022-05-11T14:10:04Z
dc.date.issued2015
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Anesteziyoloji ve Reanimasyon Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractAim: Laparoscopic cholecystectomy (LC) has become the standard treatment method of cholelithiasis. The chronic cholecystitis and cholelithiasis are the most common pathologies seen in gallbladder disease, accompanying hyperplastic and dysplastic lesions. Methods: 568 laparoscopic cholecystectomy procedures performed between 2008-2013 were analyzed. Clinical details and histopathological data were retrieved from the records. The variety of morphological changes in the diseased gall bladder were correlated with the clinical findings. Chronic cholecystitis and cholelithiasis were put into two groups. A single sample when taken from each neck-corpus and fundus of the gallbladder in the first group, two samples were taken from each site and gallbladder was mapped and examined as a whole in the second group. Results: The sex distribution of the cases was 525 (92.4%) and 43 (7.6%) male (F/M: 12.1). Median age was 45.5 ± 12.7 years (range: 18-82), median operative time was 60.2 minutes (range: 17-200). Indications for surgery, were chronic cholecystitis in 525 (92.4%), acute cholecystitis in33 (4.4%), and gallbladder polyps in 6 (1%). Acalculous cholecystitis was present in 2 patient(% 0.35) who were operated. Most common pathology noted in our study was chronic cholecystitis seen in 442 cases (%74). Other benign lesions were cholesterosis in 36 (%6) and acute cholecystitis in 28 (%.4). Various other associated lesions and variants of cholecystitis were also encountered. A total of six malignant lesions of gallbladder were observed, which included six cases of incidental adenocarcinomas. By increasing the sample size in gallbladder we saw an increase in the rate of metaplasia (p=0,009), dysplasia (p=0,009), epithelial hyperplasia (p=0.003), and carsinoma (p=0.008) statistically. Conclusion: By increasing the sample size in gallbladder we saw an increase in the rate of metaplasia, dysplasia and carcinoma statistically. © 2012 Düzce Medical Journal.
dc.identifier.endpage52
dc.identifier.issn1307-671X
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84955515085
dc.identifier.scopusqualityQ4
dc.identifier.startpage49
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5271
dc.identifier.volume17
dc.indekslendigikaynakScopus
dc.institutionauthorBali, İlhan
dc.institutionauthorEmir, Seyfi
dc.institutionauthorGürdal, S.Ö.
dc.institutionauthorTuran, Bünyamin Cüneyt
dc.institutionauthorYıldırım, Oğuzhan
dc.institutionauthorSakallı, Onur
dc.institutionauthorSözen, Selim
dc.language.isotr
dc.publisherDuzce University Medical School
dc.relation.ispartofDuzce Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCholecystectomy
dc.subjectGallbladder disease
dc.subjectHistopathology
dc.subjectacalculous cholecystitis
dc.subjectadult
dc.subjectage
dc.subjectaged
dc.subjectArticle
dc.subjectcholecystectomy
dc.subjectcholecystitis
dc.subjectcholelithiasis
dc.subjectclinical examination
dc.subjectcorrelation analysis
dc.subjectfemale
dc.subjectgallbladder carcinoma
dc.subjectgallbladder disease
dc.subjectgallbladder dysplasia
dc.subjectgallbladder hyperplasia
dc.subjectgallbladder metaplasia
dc.subjectgallbladder polyp
dc.subjectgallbladder tumor
dc.subjecthistopathology
dc.subjecthuman
dc.subjectincidental finding
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmedical record review
dc.subjectoperation duration
dc.subjectsample size
dc.subjectsex ratio
dc.subjecttreatment indication
dc.subjectvery elderly
dc.titleSpectrum of histopathological lesions in laparoscopic cholecystectomy specimens and incidental carcinoma rate: Our surgical and clinical experience
dc.title.alternativeLaparoskopik Kolesistektomi Spesimenlerinde Histopatolojik Lezyonlarin Spektrumu Ve Insidental Karsinom Orani: Klinik Ve Cerrahi Deneyimimiz]
dc.typeArticle

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