Doping agent naphazoline hydrochloride: Development of simple and fast voltammetric method for its determination in human serum

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Küçük Resim

Tarih

2019

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Turkish Chemical Society

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Electrochemical behavior of naphazoline hydrochloride on a carbon paste electrode that was modified with aluminium oxide nanoparticles (Al2O3NPs) was investigated in a Britton-Robinson (BR) buffer (pH 7.0) using various voltammetric techniques. The results support the presence of an irreversible and diffusion-controlled electrochemical oxidation signal of naphazoline hydrochloride which is approximately at 0.9 V vs. Ag/AgCl. A selective, accurate, and simple square-wave anodic adsorptive stripping voltammetric method was proposed for naphazoline hydrochloride detection. The linear response was within the range of 5.0 × 10-8-3.0 × 10-5 mol L-1 with a detection limit of 2.6 × 10-9 mol L-1 (0.642 ?g L-1). In addition, the proposed method was also utilized for naphazoline hydrochloride determination in human serum sample. © 2019, Turkish Chemical Society. All rights reserved.

Açıklama

Anahtar Kelimeler

Aluminum oxide nanoparticles, Doping agent, Electrochemical techniques, Human serum, Naphazoline

Kaynak

Journal of the Turkish Chemical Society, Section A: Chemistry

WoS Q Değeri

Scopus Q Değeri

Q4

Cilt

6

Sayı

1

Künye