The relationship between Spirulina platensis and selected biomechanical indicators of tibiae in rats

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dc.authorscopusid56951304500
dc.authorscopusid55921065100
dc.authorscopusid55259981200
dc.authorscopusid56320836200
dc.contributor.authorSüzer, Bayram
dc.contributor.authorSeyidoğlu, Nilay
dc.contributor.authorTüfekci, Kenan
dc.contributor.authorİnan, Sevda
dc.date.accessioned2022-05-11T14:05:15Z
dc.date.available2022-05-11T14:05:15Z
dc.date.issued2020
dc.departmentFakülteler, Veteriner Fakültesi, Temel Bilimler Bölümü, Fizyoloji Ana Bilim Dalı
dc.description.abstractThere are several dietary supplements, particularly herbal foods, that have been used in an attempt to improve bone growth. In this study, we aim at determining the effects of low- and high-doses of Spirulina platensis, a “Superfood”, on the bone growth and biomechanical indicators. Thirty Wistar rats, weighing 250 g, at the age of 7–8 weeks were assigned to three groups: The Control group (basal diet), Low-dose group (LDG; 500 mg/kg) and High-dose group (HDG; 1 000 mg/kg) of S. platensis. S. platensis was given daily by oral gavage in a 45-day-trial. At the end of the study, the right tibiae were collected and subjected to bone biomechanical tests (bone weight, bone length, maximum load, stiffness, breaking deflection, fracture toughness, post-yield displacement and yield load). Serum samples were also analysed for the calcium and phosphorus concentrations. There were significant increases in bone weight, bone length, maximum load, breaking deflection, work to fracture, post-yield displacement and yield load (P = 0.025, P = 0.019, P = 0.030, P = 0.015, P = 0.031, P = 0.028, P = 0.049, respectively), whereas stiffness non-significantly increased. However, there were no significant differences (P > 0.05) for any variables between the LDG and the HDG. Although the serum phosphorus concentrations showed no differences among any of the groups, the serum calcium concentration increased significantly in LDG compared to Control group (P=0.009; 7.14 ± 0.47 and 9.45 ± 0.67, respectively). However, no differences were observed in HDG in terms of serum calcium. In conclusion, S. platensis had positive effects on the bone growth and biomechanical bone features. Therefore, our study supports the use of S. platensis as an alternative food additive for bone growth and health in growing animals. © 2020 Czech Academy of Agricultural Sciences. All rights reserved.
dc.description.sponsorship16,074
dc.description.sponsorshipSupported by the Research Foundations of University (Project No. NKUBAP.10.GA.16.074).
dc.identifier.doi10.17221/47/2019-VETMED
dc.identifier.endpage24
dc.identifier.issn0375-8427
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85082938290
dc.identifier.scopusqualityQ3
dc.identifier.startpage18
dc.identifier.urihttps://doi.org/10.17221/47/2019-VETMED
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4934
dc.identifier.volume65
dc.identifier.wosWOS:000510840500003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorSeyidoğlu, Nilay
dc.language.isoen
dc.publisherCzech Academy of Agricultural Sciences
dc.relation.ispartofVeterinarni Medicina
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBone biomechanics
dc.subjectCalcium
dc.subjectNatural foods
dc.subjectPhosphorus
dc.subjectSerum
dc.subjectcalcium
dc.subjectcollagen
dc.subjectmagnesium
dc.subjectmineral
dc.subjectphosphorus
dc.subjectSpirulina extract
dc.subjectadult
dc.subjectanimal experiment
dc.subjectanimal model
dc.subjectanimal tissue
dc.subjectArthrospira platensis
dc.subjectArticle
dc.subjectbiomechanics
dc.subjectblood sampling
dc.subjectbone density
dc.subjectbone growth
dc.subjectbone length
dc.subjectbone metabolism
dc.subjectcalcium blood level
dc.subjectcomparative study
dc.subjectcontrolled study
dc.subjectdietary supplement
dc.subjectmale
dc.subjectnonhuman
dc.subjectphosphate blood level
dc.subjectrat
dc.subjecttibia
dc.titleThe relationship between Spirulina platensis and selected biomechanical indicators of tibiae in rats
dc.typeArticle

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