An ITO Based Disposable Biosensor for Ultrasensitive Analysis of Retinol Binding Protein

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dc.authorscopusid56029590100
dc.authorscopusid6602429563
dc.authorscopusid6506764918
dc.authorwosidSezgintürk, Mustafa Kemal/AAY-1439-2021
dc.contributor.authorSayıklı Şimşek, Çiğdem
dc.contributor.authorTeke, Mustafa
dc.contributor.authorSezgintürk, Mustafa Kemal
dc.date.accessioned2022-05-11T14:29:53Z
dc.date.available2022-05-11T14:29:53Z
dc.date.issued2014
dc.departmentFakülteler, Fen Edebiyat Fakültesi, Kimya Bölümü
dc.description.abstractA highly sensitive electrochemical biosensor based on anti-RBP biorecognition capable to analyze concentrations of retinol binding protein (RBP) was developed. The construction of the biosensor interfaces was carefully characterized by techniques such as electrochemistry, EIS, and scanning electron microscopy. In order to characterize impedance data, Kramers-Kronig Transform was performed on the experimental impedance data. Besides, for an immunosensor system the Single Frequency Impedance technique was firstly used for the characterization of the interaction between RBP and anti-RBP. Finally, artificial serum samples spiked with RBP were analyzed by the proposed ITO based immunosensor to investigate the usefulness of the biosensor for early biomarker diagnosis.
dc.description.sponsorshipTUBITAK (The Scientific and Technological Research Council of Turkey)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [109 T 172]; Namik Kemal University Scientific Research Projects FundNamik Kemal University [NKU-BAP.00.10.YL.13.03]; Namik Kemal University Scientific and Technological Research CenterNamik Kemal University; Mugla Sitki Kocman University Scientific Research Projects FundMugla Sitki Kocman University [12/137]
dc.description.sponsorshipThe financial supports from TUBITAK (The Scientific and Technological Research Council of Turkey, Project number: 109 T 172), Namik Kemal University Scientific Research Projects Fund (Project Number: NKU-BAP.00.10.YL.13.03), Namik Kemal University Scientific and Technological Research Center, and Mugla Sitki Kocman University Scientific Research Projects Fund (Project number: 12/137) are gratefully acknowledged.
dc.identifier.doi10.1002/elan.201300443
dc.identifier.endpage339
dc.identifier.issn1040-0397
dc.identifier.issn1521-4109
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84894355502
dc.identifier.scopusqualityQ2
dc.identifier.startpage328
dc.identifier.urihttps://doi.org/10.1002/elan.201300443
dc.identifier.urihttps://hdl.handle.net/20.500.11776/7162
dc.identifier.volume26
dc.identifier.wosWOS:000331982500014
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorSayıklı Şimşek, Çiğdem
dc.institutionauthorSezgintürk, Mustafa Kemal
dc.language.isoen
dc.publisherWiley-V C H Verlag Gmbh
dc.relation.ispartofElectroanalysis
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectRetinol binding protein
dc.subjectITO
dc.subjectSingle frequency impedance
dc.subjectBiosensor
dc.subjectBiomarker
dc.subjectIndium-Tin Oxide
dc.subjectVitamin-A
dc.subjectSurrogate Measure
dc.subjectElectrodes
dc.subjectCatecholamine
dc.subjectChildren
dc.subjectKidney
dc.titleAn ITO Based Disposable Biosensor for Ultrasensitive Analysis of Retinol Binding Protein
dc.typeArticle

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