Applications of electrochemical immunosensors for early clinical diagnostics

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dc.authorscopusid56372853400
dc.authorscopusid6506764918
dc.authorwosidSezgintürk, Mustafa Kemal/AAY-1439-2021
dc.contributor.authorBahadır, Elif Burcu
dc.contributor.authorSezgintürk, Mustafa Kemal
dc.date.accessioned2022-05-11T14:12:18Z
dc.date.available2022-05-11T14:12:18Z
dc.date.issued2015
dc.departmentRektörlüğe Bağlı Bölümler, Rektörlük, Bilimsel ve Teknolojik Araştırmalar Uygulama ve Araştırma Merkezi
dc.departmentFakülteler, Fen Edebiyat Fakültesi, Kimya Bölümü
dc.description.abstractCancer and cardiovascular diseases are the major threats to global health. Hence, there is a growing demand for a range of portable, rapid and low cost biosensing devices for the detection of these diseases. Electrochemical immunosensors are simple, rapid, reliable and inexpensive devices and they have sensitive detection limits to monitor both levels of the biomarkers in normal and patient serum. Due to the specific binding of antibody to its corresponding antigen, immunosensors based on antibody antigen interaction are one of the most widely used analytical techniques in the quantitative detection of these diseases. The changed levels of markers in patients are associated with diseases. In this article the biosensors and biomarkers, which were commonly used in terms of monitoring the diagnosis and treatment of cancer and cardiac diseases, are reviewed. In addition, the developed biosensors are compared in terms of precision, reproducibility, regeneration, stability and specificity. (C) 2014 Elsevier B.V. All rights reserved.
dc.description.sponsorshipTUBITAK (The Scientific and Technological Research Council of Turkey)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [113 Z 678]
dc.description.sponsorshipThe support from TUBITAK (The Scientific and Technological Research Council of Turkey, Project number: 113 Z 678) is greatly acknowledged.
dc.identifier.doi10.1016/j.talanta.2014.08.063
dc.identifier.endpage174
dc.identifier.issn0039-9140
dc.identifier.issn1873-3573
dc.identifier.pmid25476294
dc.identifier.scopus2-s2.0-84907545944
dc.identifier.scopusqualityQ1
dc.identifier.startpage162
dc.identifier.urihttps://doi.org/10.1016/j.talanta.2014.08.063
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5494
dc.identifier.volume132
dc.identifier.wosWOS:000349278900024
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorBahadır, Elif Burcu
dc.institutionauthorSezgintürk, Mustafa Kemal
dc.language.isoen
dc.publisherElsevier Science Bv
dc.relation.ispartofTalanta
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBiosensor
dc.subjectCancer biomarkers
dc.subjectImmunosensor
dc.subjectElectrochemical biosensors
dc.subjectEarly diagnosis
dc.subjectProstate-Specific Antigen
dc.subjectLabel-Free Immunosensor
dc.subjectSelf-Assembled Monolayers
dc.subjectScreen-Printed Electrode
dc.subjectCardiac Troponin-T
dc.subjectSensitive Amperometric Immunosensor
dc.subjectSignal Amplification Strategy
dc.subjectGlassy-Carbon Electrode
dc.subjectModified Gold Electrode
dc.subjectMesoporous Silica Nanoparticles
dc.titleApplications of electrochemical immunosensors for early clinical diagnostics
dc.typeReview Article

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