Association analyses of oxidative stress, aerobic capacity, daily physical activity, and body composition parameters in patients with mild to moderate COPD

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dc.authorid0000-0001-6404-4510
dc.authorscopusid23049681600
dc.authorscopusid23053121600
dc.authorscopusid55515412500
dc.authorscopusid55945338300
dc.authorscopusid55945141700
dc.authorscopusid7004455014
dc.authorscopusid8930904600
dc.authorwosidsener, umit/AAZ-7728-2020
dc.authorwosidUcok, Kagan/J-9685-2015
dc.contributor.authorGenç, Abdurrahman
dc.contributor.authorUçok, Kağan
dc.contributor.authorŞener, Ümit
dc.contributor.authorKoyuncu, Tulay
dc.contributor.authorAkar, Olcay
dc.contributor.authorÇelik, Sefa
dc.contributor.authorÜnlü, Mehmet
dc.date.accessioned2022-05-11T14:41:22Z
dc.date.available2022-05-11T14:41:22Z
dc.date.issued2014
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Fizyoloji Ana Bilim Dalı
dc.description.abstractBackground/aim: To investigate total oxidant and antioxidant status, maximal aerobic capacity, daily physical activity, pulmonary functions, and body composition changes, as well as the associations among these parameters, in patients with mild to moderate chronic obstructive pulmonary disease (COPD) versus healthy controls. Materials and methods: The study included 30 male patients newly diagnosed with COPD and 30 body mass index-matched, nonsmoker male controls. Maximal aerobic capacity, daily physical activity, total oxidant and antioxidant status, pulmonary function tests, body composition, and anthropometric parameters were measured. Results: Maximal aerobic capacity and total antioxidant values were lower in patients with COPD compared to the controls. The total oxidant value, body fat percentage, and waist/hip ratio were higher in patients with COPD than in the healthy controls. There was a moderately negative correlation between the total oxidant value and the maximal aerobic capacity, while there was a moderately positive correlation between the total antioxidant values and maximal aerobic capacity in patients with COPD. Conclusion: Low aerobic capacity, increased oxidative stress, and adiposity are related to impaired pulmonary functions in patients with mild to moderate COPD and might have a role in the pathogenesis of COPD.
dc.description.sponsorshipAfyon Kocatepe University Scientific Research Projects CommitteeAfyon Kocatepe University [09.TIP.06]
dc.description.sponsorshipThis study was supported by the Afyon Kocatepe University Scientific Research Projects Committee (Project No.: 09.TIP.06).
dc.identifier.doi10.3906/sag-1308-65
dc.identifier.endpage979
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue6en_US
dc.identifier.pmid25552149
dc.identifier.scopus2-s2.0-84908068279
dc.identifier.scopusqualityQ3
dc.identifier.startpage972
dc.identifier.urihttps://doi.org/10.3906/sag-1308-65
dc.identifier.urihttps://hdl.handle.net/20.500.11776/9162
dc.identifier.volume44
dc.identifier.wosWOS:000344155900010
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorŞener, Ümit
dc.language.isoen
dc.publisherTubitak Scientific & Technical Research Council Turkey
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectChronic obstructive pulmonary disease
dc.subjectmaximal aerobic capacity
dc.subjectoxidative stress
dc.subjectdaily physical activity
dc.subjectbody fat
dc.subjectObstructive Pulmonary-Disease
dc.subjectResting Metabolic-Rate
dc.subjectAnthropometric Measurements
dc.subjectAntioxidant Balance
dc.subjectFitness Parameters
dc.subjectObese Adults
dc.subjectOxidant
dc.subjectRehabilitation
dc.subjectPrevalence
dc.subjectValidation
dc.titleAssociation analyses of oxidative stress, aerobic capacity, daily physical activity, and body composition parameters in patients with mild to moderate COPD
dc.typeArticle

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