İnvaziv Aspergilloz Tedavisi
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Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Namık Kemal Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
İnvaziv aspergilloz (İA), Aspergillus türü mantarların neden olduğu genellikle immünyetmezlikli hastalarda görülen ve yüksek mortalite ile seyreden bir enfeksiyon hastalığıdır. En sık akciğer etkilenmekle birlikte mantar vücudun diğer organlarına da yayılarak hastalık yapabilir. Tedavisinde halen vorikonazol birinci seçenek antifungaldir. Vorikonazol alamayacak ya da vorikonazole cevap vermeyen hastalarda tedavide alternatif olarak isavukonazol, itrakonazol, amfoterisin B lipid formülasyonu, itrakonazol, kaspofungin, mikafungin ve posakonazol kullanılabilir. Bu yazıda invaziv aspergilloz tedavisi gözden geçirilmiştir.
Invasive aspergillosis (IA) is an infectious disease caused by Aspergillus species, is usually seen in patients with immune deficiency and has been associated with high mortality rate. IA most commonly affects the lungs, but Aspergillus can also spread throughout the body and cause infection in other organs. Voriconazole is the firstline antifungal agent in the treatment of invasive aspergillosis. Other antifungal agents including isavuconazole, lipid amphotericin formulations, itraconazole, caspofungin, micafungin, and posaconazole can be used to treat IA in patients who can not take voriconazole or who have not responded to voriconazole. In this article, the treatment of invasive aspergillosis was reviewed.
Invasive aspergillosis (IA) is an infectious disease caused by Aspergillus species, is usually seen in patients with immune deficiency and has been associated with high mortality rate. IA most commonly affects the lungs, but Aspergillus can also spread throughout the body and cause infection in other organs. Voriconazole is the firstline antifungal agent in the treatment of invasive aspergillosis. Other antifungal agents including isavuconazole, lipid amphotericin formulations, itraconazole, caspofungin, micafungin, and posaconazole can be used to treat IA in patients who can not take voriconazole or who have not responded to voriconazole. In this article, the treatment of invasive aspergillosis was reviewed.
Açıklama
Anahtar Kelimeler
Invasive aspergillosis, treatment, İnvaziv aspergilloz, tedavi
Kaynak
Namık Kemal Tıp Dergisi (International Journal of Basic and Clinical Medicine)
WoS Q Değeri
Scopus Q Değeri
Cilt
6
Sayı
2
