Yazar "Yaşar, Tuba Özge" seçeneğine göre listele
Listeleniyor 1 - 9 / 9
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe A urolithiasis case related to nutritional disorders in a male cat(Agricultural Research Communication Centre, 2017) Yaşar, Tuba Özge; Özkan, KadircanUrolithiasis was diagnosed by clinical and radiographic examination in a 2.5 year old male cat. Under general anesthesia routine laparotomy procedure was applied. Urine was taken out from the filled bladder and vesicotomy was performed. Crystalloid structures (uroliths) found in the bladder and urethra was removed. Urinary system antiseptic and antibiotics were administered during the postoperative period. Owner of the patient was informed about a proper feeding in order to avoid relapse. As a result, the diet of the castrated male cats requires special attention in order to avoid calculi formation. Low-protein foods which prevent crystallization in urinary tract must be preferred. Urine pH should occasionally be checked and water consumption should be encouraged by providing a source of fresh water.Öğe Comparative efficacy of propofol and clove oil as sedatives in transportation of Jack Dempsey fish (Rocio octofasciata)(2020) Yaşar, Tuba Özge; Yağcılar, Çetin; Yardımcı, MehmetAim: The aim of this research was to examine the efficacies of propofoland clove oil to decrease the metabolic activity during transportationin order to determine optimal protocols for sedation of fish.Materials and Methods: 126 Jack Dempsey fish were used in thisresearch. Control (n:42), propofol (n:42) and clove oil (n:42) groupsplaced into closed clear plastic fish bags filled with three litres ofoxygen per litre of water and supplemented with 0.1 ml/L of propofoland clove oil. Respiratory rates, induction and recovery times,feed intake and color-changing times were measured while reactionsto light, vibration and touch were scored for sensitivity controls.Results: According to the results, the decrease of respiratory ratesper minute (67.26 ± 6.3, 50.26 ± 9.4, 36.52 ± 4.6, 11.74 ± 4.8, 7.10 ±3.5, 4.50 ± 2.2, 3.69 ±1.5) and recovery time respiratory rates (frequencyper minute) of the propofol group (80.12 ± 1.84) differed fromthe control and clove oil groups (p ? 0.05). Regarding the sensibilitycontrols, propofol group was less sensible to light, vibration and touch.Conclusion: Considering its low cost and easy availability, sincepropofol has been found to be more suitable and clove oil was moreineffective than propofol, therefore propofol can be recommended asa priority in the transport of aquarium fish.Öğe Determination of the average intraocular pressure values, optimum anesthesia dose and phenotypic characteristics in Oscar fish (Astronotus ocellatus)(2021) Yaşar, Tuba Özge; Yağcılar, Çetin; Yardımcı, MehmetThis research was carried out to determine the intraocular pressure values, optimum anesthesia dose and phenotypic characteristics in Oscar fish (Astronotus ocellatus). A total of 11 adult, male Oscar fish were used in the study. Optimum anesthesia dose, pre-and post-anesthesia intraocular pressure values and phenotypic measurements (total length, fork length, standard length, dorsal fin base length, head length, body length, eye diameter, body depth, pectoral length, pelvic fin bottom length, anal fin bottom length) were determined and reference values specific to this fish species were obtained by performing a statistical analysis. When exposed to 3 cc/L of the concentrations, fish achieved a deep state of anesthesia (induction time 1.31 min; recovery time 6.42 min). The most balanced anesthesia without risking vital functions was achieved using Clove oil with a dose of 2.5 cc/L. Compared to the other dimensions, total length, fork length and standard length were the most consistent body measurements with high positive correlations. No statistically significant difference (p > 0.05) was seen in both eyes between the intraocular pressure values before (5.36-5.86) and after (5.59-5.36) anesthesia. It is recommended that the ideal concentration of clove oil was 2.5 cc/L to reduce stress and injury damage during handling procedures. Additionally, intraocular pressure values, body measurements and Clove oil optimum anesthesia dose obtained in this study can be used as reference values for Oscar fish raised in aquarium conditions.Öğe Dişi ve Erkek Lepistes Balıklarında (Poecilia reticulata) Farklı Dozlarda Uygulanan Karanfil Yağının Anestezik Etkisi(2020) Yağcılar, Çetin; Yaşar, Tuba Özge; Yardımcı, MehmetBu çalışmada, erkek ve dişi lepistes (Poecilia reticulata) balıklarda farklı oranlardauygulanan karanfil yağının anestezik etkisinin değerlendirilmesi amaçlanmıştır. Anesteziketkinin değerlendirilmesi amacıyla yetişkin erkek ve dişi balıklar kullanılmıştır. Karanfil yağıkonsantrasyonları erkek ve dişi balıklarda ayrı ayrı olarak litreye 0.5, 1, 1.5 ve 2 ml olacak şekildedozlar belirlenmiştir. Deneme sırasında balıklarda anesteziye giriş ve çıkış süreleri ile canlıağırlık ve toplam boy uzunluğu ölçülmüştür. Denemeden 48 saat sonra ise farklı dozlardauygulanan karanfil yağının balıklardaki etkileri gözlenmiştir. Anesteziye giriş süresi erkeklerdesırasıyla 154.93±6.2, 136.07±5.3 ve 110.40±3.5 sn, anesteziden çıkış 330.20±12.8, 443.20±29.4ve 603.87±17.0 sn olarak tespit edilirken; dişilerde anesteziye giriş süresi 123.03±4.9, 109.50±3.2ve 89.20±3.0 sn, anesteziden çıkış ise 186.20±9.0, 216.70±8.8 ve 249.67±8.9 sn olarakbelirlenmiştir. Erkek ve dişi cinsiyetler arasında anlamlı düzeyde bulunan istatistiksel fark,erkeklerin anesteziye daha geç girdikleri ve geç çıktıklarını ortaya koymuştur. Sonuç olarak,karanfil yağının lepistes erkek ve dişi balıklarda her üç dozda da etkin olarak kullanılabileceği veherhangi bir zararlı etkiye yol açmadığı görülmüştür.Öğe Efficacy of novel albendazole salt formulations against secondary cystic echinococcosis in experimentally infected mice(Cambridge Univ Press, 2020) Vural, G.; Yardımcı, Mehmet; Koçak, Melek; Yaşar, Tuba Özge; Kurt, A.; Harem, İsmail Şah; Casulli, AdrianoIn this study, we evaluated the efficacy, expressed as a mean weight decrease of the whole echinococcal cyst mass, of novel benzimidazole salt formulations in a murine Echinococcus granulosus infection model. BALB/c mice were intraperitoneally infected with protoscoleces of E. granulosus (genotype G1). At 9 months post-infection, treatment with albendazole (ABZ), ricobendazole (RBZ) salt formulations, and RBZ enantiomer salts (R)-(+)-RBZ-Na and (S)-(-)-RBZ-Na formulations were initiated. Drugs were orally applied by gavage at 10 mg kg(-1) body weight per day during 30 days. Experimental treatments with benzimidazole sodium salts resulted in a significant reduction of the weight of cysts compared to conventional ABZ treatment, except for the (S)-(-)-RBZ-Na enantiomer formulation. Scanning electron microscopy and histological inspection revealed that treatments impacted not only the structural integrity of the parasite tissue in the germinal layer, but also induced alterations in the laminated layer. Overall, these results demonstrate the improved efficacy of benzimidazole salt formulations compared to conventional ABZ treatment in experimental murine cystic echinococcosis.Öğe MS-222, propofol ve karanfil yağının Daphnia magna’ larda anestezik etkisinin kalp atım oranlarına göre değerlendirilmesi(2023) Yaşar, Tuba Özge; Yağcılar, ÇetinGünümüzde Avrupa Birliği (EU), Amerikan Test ve Malzeme Kurumu (ASTM), Uluslararası Standardizasyon Teşkilatı (ISO), Ekonomik Kalkınma ve İşbirliği Örgütü (OECD) gibi pek çok kuruluş; bazı kimyasal maddelerin, ilaçların gerek çevreye, gerekse canlılara olan etkilerini invivo koşullarda araştırılması amacıyla Daphnia magna adı verilen sucul omurgasız canlıdan yararlanılmaktadır. Su ürünleri yetiştiriciliğinde karanfil yağı, MS 222 ve propofol yaygın bir şekilde kullanılan anestezik maddelerdendir. Ancak bu anestezik maddelerin tatlı su ortamında bulunan kabuklu canlılar için etkileri hakkında çok fazla bilgi yoktur. Yapılan bu çalışmada, anestezik etkisi olan, MS-222, propofol, ve karanfil yağının su piresi olarak bilinen Daphnia magna’ larda kısa süredeki kalp atım sayısında oluşturduğu farklar ve hayatta kalma etkisi araştırılmıştır. Anestezik maddeler 0.1-0.01-0.001 ml/L olarak uygulanmış ve çalışmanın 1., 3., ve 5. saatlerinde su pirelerinin kalp atım sayıları ve ölüm oranları değerlendirilmiştir. Deneme süresince elde edilen verilere göre kullanılan üç farklı anestezik maddenin kalp atım sayıları ve ölüm oranları üzerindeki etkileri bakımından anlamlı bir fark olduğu görülmüştür (p<0.05). Çalışmanın sonucu olarak düşük oranlarda bile bu üç farklı anestezik maddenin tatlı su ortamlarında bulunan omurgasız canlılar için toksik bir etki yaratabileceği ve ekolojik dengeyi etkileyebileceği görülmüştür.Öğe Trends towards the use of natural anesthetics in fish(İstanbul Veteriner Hekimler Odası, 2022) Yaşar, Tuba Özge; Yardımcı, MehmetAnesthesia is generally defined as the loss of sensation caused by a pharmacological agent resulting from the suppression of the nervous system. Anesthetic agents are used to reduce stress, facilitate surgical operations requiring prolonged immobilization, in transportation, classification, handling, sorting, tagging, grading, weighing, measuring, or vaccination in fish. In order to talk about an adequate level of anesthesia, signs such as loss of balance, relaxation in muscle tone, decreased respiration, and inability to respond to stimuli must be observed in the fish. A good anesthetic agent must not have toxic side effects, be able to be eliminated from the body in a short time, not have permanent physiological, immunological, or behavioral effects. In order to determine the optimal anesthesia dose, exposure time, and maximize the drug’s efficacy in fish, the size of the fish and the characteristics of the water it is in need to be determined beforehand. There are two types of commercial anesthetics, natural and synthetic. Although chemical anesthetics are commonly used for fish, there has been a recent trend towards the use of natural anesthetics due to safety, residue problems, accumulation in the fish body, and side effects. These new herbal anesthetics have more favorable properties for the health of both fish species and the people who consume them.Öğe Unilateral Hypermature Cataract and Uveitis in Dwarf Campbell's Hamster (Phodopus campbelli)(Agricultural Research Communication Centre, 2022) Yaşar, Tuba ÖzgeBackground: In the ophthalmological examination of a 1.5-year-old male dwarf Campbell hamster, who was examined with complaints of photophobia, pain, weakness and whitening of the eye color, hypermature cataract and chronic uveitis were observed in the left eye. Methods: Local antibiotic therapy was administered to the patient for the first ten days in order to eliminate a possible microbial agent. In addition, local NSAI drugs were applied to reduce pain and inflammation. Then, peros Prednol (methylprednisolone) was administered at a dose of 0.5 mg/kg for the first ten days and 1 mg/kg for the next ten days in order to suppress the inflammation associated with uveitis. The patient’s body weight and intraocular pressure were measured before the treatment. During the treatment, intraocular pressure values were checked every day. During this period, the patient was fed ad libitum at normal room temperature, in his own cage. Result: As a result of the treatment applied to the patient, who was followed up for more than a month, symptoms such as pain, photophobia and blepharospasm disappeared and the patient’s eating and drinking status improved compared to the past. However, increasing dose of Prednol did not have the expected effect on intraocular pressure values. Due to the very small size of the hamster eye in the treatment of hypermature cataracts, lens removal cannot be performed as easily as in other species. © 2022, Agricultural Research Communication Centre. All rights reserved.Öğe Veteriner cerrahide lokal kök hücre uygulamaları(2023) Yaşar, Tuba Özge; Perk, CemKök hücreler; organizmada organların ve dokuların yapısını oluşturan ana hücrelerdir. Bu sebeple ihtiyaç halinde hasar gören tüm doku ve organlara dönüşüm sağlayarak bunların onarılmasında ciddi rol almaktadır. İnsan hekimliğinde son 10 yılda yaygın bir kullanım alanı bulan kök hücre tedavisi, günümüzde veteriner tıbbında da uygulanmaktadır. Mezenkimal kök hücreler hayvanlarda pek çok hastalığın tedavisinde kullanılmaktadır. Steril ortamlarda kemik iliği, kordon kanı, ve yağ dokudan elde edildikten sonra sıvı azot tanklarında dondurularak saklanmaktadır. Hastaya uygulama öncesinde enjeksiyona hazır hale getirilerek taze olarak verilmektedir. Kök hücreler, hayvanlara lokal enjeksiyon ya da intra venöz yolla uygulanmaktadır. Viral ve enfeksiyöz hastalıklarda canlıda immun sistemin güçlendirilmesi amacıyla intravenöz yolla mezenkimal kök hücreler kullanılmaktadır. Çeşitli ortopedik, nörolojik ve oftalmolojik hastalıkların tedavisinde ise kök hücreler lokal olarak uygulanmaktadır. Sunulan bu çalışmada, 8 köpek, 6 kedi üzerinde toplam 14 vakaya ait veriler yer almaktadır. 7 ortopedik, 5 nörolojik, 2 oftalmolojik vakada lokal yolla uygulanan mezenkimal kök hücre tedavisi ve elde edilen sonuçlar değerlendirilmiştir. Ortopedik ve nörolojik vakalarda büyük oranda iyileşme sağlandığı, oftalmolojik olgularda da belirgin düzelmeler olduğu saptanmıştır.
