Investigation of the default mode network of the brain during Alzheimer's disease by minimum spanning tree

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dc.authorscopusid6603952578
dc.contributor.authorÇiftçi, Koray
dc.date.accessioned2022-05-11T14:16:00Z
dc.date.available2022-05-11T14:16:00Z
dc.date.issued2011
dc.departmentFakülteler, Çorlu Mühendislik Fakültesi, Biyomedikal Mühendisliği Bölümü
dc.description2011 IEEE 19th Signal Processing and Communications Applications Conference, SIU 2011 -- 20 April 2011 through 22 April 2011 -- Antalya -- 85528
dc.description.abstractThis study analyzes the connectivity pattern of the default mode network (DMN) in patients with Alzheimer's disease (AD) in comparison with young and elderly controls using the minimum spanning tree (MST). The findings revealed that the alterations of the basic structure represented by the MST might provide valuable insights about the physiopathology of the disease. Additionally, by making use of the MST for functionally clustering the DMN, it was shown that the functional subnetworks comprising the DMN differed among the three subject groups. Nonetheless, there were intact prefrontal and temporal networks in elderly controls and AD patients, as well. The analysis shows that the DMN of the AD patients exhibit a higher segregation. We conclude that the MST can be used effectively for analyzing cortical networks. © 2011 IEEE.
dc.identifier.doi10.1109/SIU.2011.5929792
dc.identifier.endpage880
dc.identifier.isbn978-1457704635
dc.identifier.scopus2-s2.0-79960398126
dc.identifier.startpage877
dc.identifier.urihttps://doi.org/10.1109/SIU.2011.5929792
dc.identifier.urihttps://hdl.handle.net/20.500.11776/6145
dc.indekslendigikaynakScopus
dc.institutionauthorÇiftçi, Koray
dc.language.isotr
dc.relation.ispartof2011 IEEE 19th Signal Processing and Communications Applications Conference, SIU 2011
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAlzheimer
dc.subjectAlzheimer's disease
dc.subjectBasic structure
dc.subjectConnectivity pattern
dc.subjectCortical network
dc.subjectMinimum spanning trees
dc.subjectPhysiopathology
dc.subjectSubnetworks
dc.subjectTemporal networks
dc.subjectParallel architectures
dc.subjectPlant extracts
dc.subjectSignal processing
dc.subjectNeurodegenerative diseases
dc.titleInvestigation of the default mode network of the brain during Alzheimer's disease by minimum spanning tree
dc.title.alternativeAlzheimer hastali?inda beyi?n varsayilan durum a?inin en küçük örten a?aç i?le i?ncelenmesi?]
dc.typeConference Object

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