The relationship between nondipper hypertension and triglyceride glucose index

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dc.authorwosidEmlek, Nadir/HNI-4345-2023
dc.contributor.authorEmlek, Nadir
dc.contributor.authorAydın, Cihan
dc.date.accessioned2023-05-06T17:23:33Z
dc.date.available2023-05-06T17:23:33Z
dc.date.issued2022
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractNondipper hypertensive patients have an increased incidence of damage to end organs, including the brain, heart, and kidney, and a worse cardiovascular prognosis. The triglyceride glucose (TyG) index is a reliable indicator of insulin resistance (IR) and is closely related to the traditional risk factors of cardiovascular disease. To the best of our knowledge, whether there is a relationship between the TyG index and impaired diurnal blood pressure (BP) has not been investigated. This study aimed to compare the TyG index between normotensive, nondipper, and dipper hypertensive patients. A total of 1037 patients grouped according to the results of ambulatory BP monitoring were included, with group 1 including dipper hypertensive (n = 368), group 2 including nondipper hypertensive (n = 496), and group 3 including normotensive control (n = 173) patients. In both the univariate and multivariate logistic regression analyses, TyG index [odds ratio (OR), 4.656; 95% confidence interval (CI), 3.014-7.193; P < 0.001], age (OR, 1.011; 95% CI, 1.002-1.021; P = 0.018), and glomerular filtration rate (GFR) (OR, 0.979; 95% CI, 0.971-0.987; P < 0.001) were independent predictors of nondipper hypertension (HT). In the ROC analysis, a TyG index cutoff value of at least 4.74 predicted nondipper hypertensive patients with a sensitivity of 59.7%, and a specificity of 59.9% [area under the curve = 0.647 (0.614-0.680); 95% CI; P < 0.001]. We showed that TyG index, age, and GFR are independent predictors in patients with nondipper HT. TyG index, a simple, cost-effective, and rapid tool can predict the nondipper pattern in essential HT.
dc.identifier.doi10.1097/MBP.0000000000000618
dc.identifier.endpage390
dc.identifier.issn1359-5237
dc.identifier.issn1473-5725
dc.identifier.issue6en_US
dc.identifier.pmid36094366
dc.identifier.scopus2-s2.0-85141890556
dc.identifier.scopusqualityQ2
dc.identifier.startpage384
dc.identifier.urihttps://doi.org/10.1097/MBP.0000000000000618
dc.identifier.urihttps://hdl.handle.net/20.500.11776/12145
dc.identifier.volume27
dc.identifier.wosWOS:000878626900004
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAydın, Cihan
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofBlood Pressure Monitoring
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectnondipper hypertensive
dc.subjecttriglyceride glucose index
dc.subjectSerum Uric-Acid
dc.subjectInsulin-Resistance
dc.subjectBlood-Pressure
dc.subjectTyg Index
dc.subjectDipper
dc.subjectPopulation
dc.subjectPrediction
dc.subjectRisk
dc.titleThe relationship between nondipper hypertension and triglyceride glucose index
dc.typeArticle

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