Treatment of chronic inflammatory demyelinating polyneuropathy with high dose intravenous methylprednisolone monthly for five years: 10-Year follow up

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dc.authorid0000-0002-7671-7097
dc.authorid0000-0002-0094-5624
dc.authorscopusid16634650500
dc.authorscopusid25624536100
dc.authorscopusid14047809600
dc.authorscopusid22952478800
dc.authorscopusid54792462000
dc.authorscopusid56024456700
dc.authorscopusid54791952300
dc.authorwosidbilgiç, adnan/AAX-3070-2021
dc.contributor.authorBoru, Ülkü Türk
dc.contributor.authorErdoğan, Hulya
dc.contributor.authorAlp, Recep
dc.contributor.authorTasdemir, Mustafa
dc.contributor.authorYıldırım, Serhan
dc.contributor.authorBilgiç, Adnan
dc.contributor.authorArslan, Alper
dc.date.accessioned2022-05-11T14:40:15Z
dc.date.available2022-05-11T14:40:15Z
dc.date.issued2014
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı
dc.description.abstractObjective: Although various modalities of treatment of chronic inflammatory demyelinating polyradiculopathy (CIDP) there are not any treatment protocol agreed. Materials and methods: We retrospectively evaluated the 20 CIDP patients (14 male, 6 female). Five patients were excluded from the study because they could not continue their treatments due to various problems during the treatment. The remaining 15 patients treated with monthly high dose intravenous methyl prednisolone for five years (IVMP) and followed up for 10 years. Results: The mean age of the patients was 48.1 +/- 14.6 years. The mean duration of disease was 6.8 +/- 3.1 years. We were found statistically significant difference between the pre-treatment and sixth month modified Rankin scores (p <0.001). Similarly, significant improvement was observed at the end of first, fourth and fifth years of treatment. Statistically significant difference was found between baseline and tenth year modified Rankin scores of 12 patients who were treated with only IVMP during 10 years follow-up. Conclusion: Long-term monthly IVMP pulse therapy seems to be very effective in the treatment of CIDP. (C) 2014 Elsevier B.V. All rights reserved.
dc.identifier.doi10.1016/j.clineuro.2014.01.001
dc.identifier.endpage93
dc.identifier.issn0303-8467
dc.identifier.issn1872-6968
dc.identifier.pmid24529237
dc.identifier.scopus2-s2.0-84893406682
dc.identifier.scopusqualityQ2
dc.identifier.startpage89
dc.identifier.urihttps://doi.org/10.1016/j.clineuro.2014.01.001
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8916
dc.identifier.volume118
dc.identifier.wosWOS:000332920300019
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAlp, Recep
dc.language.isoen
dc.publisherElsevier Science Bv
dc.relation.ispartofClinical Neurology and Neurosurgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectChronic inflammatory demyelinating polyradiculopathy
dc.subjectMethylprednisolone
dc.subjectPolyradiculoneuropathy
dc.subjectDexamethasone
dc.titleTreatment of chronic inflammatory demyelinating polyneuropathy with high dose intravenous methylprednisolone monthly for five years: 10-Year follow up
dc.typeArticle

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