Predictive Values of Inflammation Indexes in Predicting Mortality in Patients with COVID 19 Hospitalized in General Intensive Care Unit

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dc.contributor.authorEngin, Mesut
dc.contributor.authorYıldırım, İlker
dc.contributor.authorArar, Makbule Cavidan
dc.contributor.authorAmaç, Bişar
dc.contributor.authorAlpsoy, Şeref
dc.contributor.authorAydın, Cihan
dc.contributor.authorGültekin, Ahmet
dc.date.accessioned2023-04-20T08:07:18Z
dc.date.available2023-04-20T08:07:18Z
dc.date.issued2022
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractObjective: Causing a global pandemic, the coronavirus disease 2019 (COVID-19) has caused millions of people to become infected and many more to die. In this study we aimed to investigate whether routinely evaluated clinical and laboratory values ??can predict the mortality of patients with COVID-19 disease.Materials and Methods: In our study, routine laboratory parameters of 89 patients hospitalized in the general intensive care unit with the diagnosis of COVID 19 were retrospectively analyzed. The aggregate index of systemic inflammation (AISI) and other inflamatuar values were calculated from blood tests in patients with positive COVID-19 polymerase chain reaction test and with ground-glass opacity on lung tomography. Patients were divided into two groups as those who died (non-survivors) and those who were discharged (survivors)during the intensive care follow-ups. Results: In our study, in 48 patients who died during follow-up, the indexes of AISI, other inflamatuar paramaters and the biochemical parameters such as troponin I, d-dimer, ferritin and procalcitonin were significantly higher than in discharged patients. Hypertension and higher AISI and ferritin levels were statistically associated with reduced survival in Cox regression analysis (Hazard ration (HR): 3.176; 95% Confident interval (CI): 1.122-8.991, p=0.03, HR: 1.114; 95% CI: 1.060-1.348, p=0.042, HR=1.072;95% CI: 1.014-1.242, p=0.011, respectively.Conclusion: Inflammation indexes derived from blood tests and acute phase reactants such as ferritin can guide us in planning the treatment strategy and risk stratification in patients with COVID-19 in intensive care follow-ups. 
dc.identifier.doi10.26453/otjhs.984345
dc.identifier.endpage39
dc.identifier.issn2459-1467
dc.identifier.issue1en_US
dc.identifier.startpage32
dc.identifier.trdizinid508171
dc.identifier.urihttps://doi.org/10.26453/otjhs.984345
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/508171
dc.identifier.urihttps://hdl.handle.net/20.500.11776/11236
dc.identifier.volume7
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorAydın, Cihan
dc.institutionauthorAlpsoy, Şeref
dc.institutionauthorYıldırım, İlker
dc.institutionauthorGültekin, Ahmet
dc.institutionauthorArar, Makbule Cavidan
dc.language.isoen
dc.relation.ispartofOnline Türk Sağlık Bilimleri Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectcoronavirus 2019 disease
dc.subjectpandemic
dc.subjectblood parameters
dc.subjectinflammation
dc.titlePredictive Values of Inflammation Indexes in Predicting Mortality in Patients with COVID 19 Hospitalized in General Intensive Care Unit
dc.typeArticle

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