Does Blood Pressure Variability Affect Hypertension Development in Prehypertensive Patients?

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dc.authorscopusid8570900600
dc.authorscopusid6603926071
dc.authorscopusid36338307600
dc.authorscopusid6701557803
dc.authorscopusid7004571672
dc.authorscopusid55920765900
dc.authorscopusid9736922500
dc.contributor.authorÖzkan, Gülsüm
dc.contributor.authorUlusoy, Şükrü
dc.contributor.authorArıcı, Mustafa
dc.contributor.authorDerici, Ülver
dc.contributor.authorAkpolat, T.
dc.contributor.authorŞengül, Şule
dc.contributor.authorErdem, Yunus
dc.date.accessioned2022-05-11T14:05:03Z
dc.date.available2022-05-11T14:05:03Z
dc.date.issued2022
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractBACKGROUND: Blood pressure variability (BPV) is associated with end organ damage and cardiovascular outcomes in hypertensive patients. Prehypertensive patients frequently develop hypertension (HT). The purpose of the present study was to evaluate the effect of BPV on the development of HT. METHODS: Two hundred and seven prehypertensive patients from the Cappadocia cohort were monitored over 2 years, and 24-hour ambulatory blood pressure monitoring (ABPM), office BP, and home BP measurements were subsequently performed at 4- to 6-month intervals. BPV was calculated as average real variability (ARV) from 24-h ABPM data, home BP, and office BP measurements at first visit. The relationship was evaluated between baseline ARV and the development of HT. RESULTS: HT was diagnosed in 25.60% of subjects. Baseline 24-hour ABPM systolic blood pressure (SBP)ARV and diastolic blood pressure (DBP)ARV and home SBPARV were significantly higher in patients who developed HT than the other patients (P 0.006, 0.001 and 0.006, respectively). Baseline 24-hour ABPM SBPARV and home SBPARV exceeding the 90th percentile were identified as parameters affecting development of HT at logistic regression analysis. CONCLUSION: In conclusion, our prospective observational cohort study showed that short-term BPV in particular can predict the development of HT in the prehypertensive population. © American Journal of Hypertension, Ltd 2021. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
dc.identifier.doi10.1093/ajh/hpab125
dc.identifier.endpage78
dc.identifier.issn1941-7225
dc.identifier.issue1en_US
dc.identifier.pmid34351385
dc.identifier.scopus2-s2.0-85123323495
dc.identifier.scopusqualityQ2
dc.identifier.startpage73
dc.identifier.urihttps://doi.org/10.1093/ajh/hpab125
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4878
dc.identifier.volume35
dc.identifier.wosWOS:000743294300011
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÖzkan, Gülsüm
dc.language.isoen
dc.publisherNLM (Medline)
dc.relation.ispartofAmerican journal of hypertension
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subject24h-ABPM
dc.subjectblood pressure
dc.subjectBlood pressure variability
dc.subjectBPV
dc.subjecthypertension
dc.subjectprehypertension
dc.titleDoes Blood Pressure Variability Affect Hypertension Development in Prehypertensive Patients?
dc.typeArticle

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