Effect of a Single Dose of Deflazacort on Postoperative Pain, Swelling, and Trismus after Impacted Lower Third Molar Surgery: Randomised Clinical Trial

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dc.contributor.authorKaplan, Volkan
dc.contributor.authorCigerim, Levent
dc.contributor.authorFeslihan, Erkan
dc.contributor.authorCigerim, Saadet Cinarsoy
dc.date.accessioned2024-10-29T17:59:24Z
dc.date.available2024-10-29T17:59:24Z
dc.date.issued2024
dc.departmentTekirdağ Namık Kemal Üniversitesi
dc.description.abstractBackground and Objectives: The aim of this study was to investigate the efficacy of a single preoperative dose of deflazacort on pain, swelling, and trismus after impacted lower third molar surgery. Materials and Methods: This randomised, prospective, double-blind, split-mouth clinical study included 26 healthy individuals with bilaterally impacted lower third molars. Group 1 was given a placebo (single-dose vitamin C tablet), and group 2 was given a single 30 mg dose of deflazacort 1 h prior to surgery. Pain was evaluated using the visual analogue scale for 1 week postoperatively. Oedema (in mm) and trismus (in mm) were evaluated preoperatively and on postoperative days 2 and 7. The Mann-Whitney U test was applied for group analyses. p values < 0.05 were considered statistically significant. Results: Postoperative pain scores were significantly lower in the deflazacort group at the 6th and 12th hours after surgery (p < 0.05). There were no significant differences in trismus between the groups at any time point (p > 0.05). There was less oedema in the deflazacort group on postoperative days 2 and 7, without any statistically significant difference (p > 0.05). Conclusions: A single preoperative dose of 30 mg deflazacort was found to be clinically effective in reducing pain and oedema after extraction of impacted lower third molars.
dc.identifier.doi10.3390/medicina60081206
dc.identifier.issn1010-660X
dc.identifier.issn1648-9144
dc.identifier.issue8en_US
dc.identifier.pmid39202488
dc.identifier.scopus2-s2.0-85202504570
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.3390/medicina60081206
dc.identifier.urihttps://hdl.handle.net/20.500.11776/14725
dc.identifier.volume60
dc.identifier.wosWOS:001307339500001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMdpi
dc.relation.ispartofMedicina-Lithuania
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectdeflazacort
dc.subjectcorticosteroid
dc.subjectpain
dc.subjectswelling
dc.subjecttrismus
dc.subjectimpacted third molar surgery
dc.titleEffect of a Single Dose of Deflazacort on Postoperative Pain, Swelling, and Trismus after Impacted Lower Third Molar Surgery: Randomised Clinical Trial
dc.typeArticle

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