Barrett esophagus frequency and predictors of dysplasia or cancer in Barrett esophagus

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dc.authorscopusid6602835899
dc.authorscopusid24177559900
dc.authorscopusid57873444900
dc.contributor.authorKüçükmetin, N. T.
dc.contributor.authorTiftikçi, A.
dc.contributor.authorÇiçek, B.
dc.date.accessioned2023-04-20T08:00:15Z
dc.date.available2023-04-20T08:00:15Z
dc.date.issued2022
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractOBJECTIVE: Identificating factors associated with an increased risk for dysplasia and cancer development among patients with Barrett esophagus would aid better patient care and improve risk stratification approaches. This study aimed at examining the frequency of Barrett esophagus and factors predicting the presence of dysplasia and cancer among patients with Barrett esophagus. PATIENTS AND METHODS: Adult patients that underwent upper gastrointestinal endoscopic ex-amination for gastroesophageal complaints were screened in this retrospective, cross-sectional study; and patients diagnosed with Barrett esophagus were included in the analysis. Frequency of dysplasia/cancer and its predictors were examined. RESULTS: Among 10,404 endoscopic examinations performed during the study period, 143 patients (1.4%) were diagnosed with Barrett esophagus. Among patients with Barrett esophagus, the frequency for high-grade dysplasia, low grade dysplasia, and adenocarcinoma was 2.8%, 2.1%, and 1.4%, respectively. On multivariate analysis, age >= 55 years (OR, 11.1 [95%CI: 2.0-61.4], p=0.006) and long segment Barrett esophagus (OR, 5.7 [95%CI: 1.2-27.8], p=0.031) emerged as significant independent predictors for dysplasia/cancer. CONCLUSIONS: Frequency of Barrett esophagus in our population seems to be different than figures reported from different geographical regions. Advanced age and long Barrett segment on endoscopic examination are associated with the presence of concomitant dysplasia/cancer on pathological examination. Larger studies with prospective methodology are warranted.
dc.identifier.endpage5889
dc.identifier.issn1128-3602
dc.identifier.issue16en_US
dc.identifier.pmid36066163
dc.identifier.scopus2-s2.0-85137217232
dc.identifier.scopusqualityQ2
dc.identifier.startpage5884
dc.identifier.urihttps://hdl.handle.net/20.500.11776/10782
dc.identifier.volume26
dc.identifier.wosWOS:000877558000032
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKüçükmetin, N. T.
dc.language.isoen
dc.publisherVerduci Publisher
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBarrett Esophagus
dc.subjectDysplasia
dc.subjectEsophageal Cancer
dc.subjectUpper Gastrointestinal Endoscopy
dc.subjectGastroesophageal-Reflux Disease
dc.subjectNeoplastic Progression
dc.subjectPrevalence
dc.subjectDiagnosis
dc.titleBarrett esophagus frequency and predictors of dysplasia or cancer in Barrett esophagus
dc.typeArticle

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