Clinical usefulness of red cell distribution width to angiographic severity and coronary stent thrombosis

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dc.authorid0000-0002-6866-0625
dc.authorscopusid56919292900
dc.authorscopusid56195421000
dc.authorscopusid12808672900
dc.authorscopusid25626826200
dc.authorscopusid37058172000
dc.authorscopusid16643711000
dc.authorscopusid16551053800
dc.authorwosidZencirci, Ertugrul/X-6487-2018
dc.contributor.authorErdem, Aysun
dc.contributor.authorCeylan, Ufuk Sadık
dc.contributor.authorEsen, Aycan
dc.contributor.authorZencirci, Ertugrul
dc.contributor.authorTopçu, Birol
dc.contributor.authorÖzden, Kivilcim
dc.contributor.authorYesilcimen, Kemal
dc.date.accessioned2022-05-11T14:41:21Z
dc.date.available2022-05-11T14:41:21Z
dc.date.issued2016
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Biyoistatistik Ana Bilim Dalı
dc.description.abstractBackground: Red cell distribution width (RDW) is a quantitative measurement and shows heterogeneity of red blood cell size in peripheral blood. RDW has recently been associated with cardiovascular events and cardiovascular diseases, and it is a novel predictor of mortality. In this study, we aimed to evaluate the clinical usefulness of measuring RDW in patients with coronary stent thrombosis. Patients and methods: We retrospectively reviewed 3,925 consecutive patients who presented with acute coronary syndrome and who underwent coronary angiography at the Siyami Ersek Hospital between May 2011 and December 2013. Of the 3,925 patients, 73 patients (55 males, mean age 59 +/- 11 years, 55 with ST elevated myocardial infarction) with stent thrombosis formed group 1. Another 54 consecutive patients who presented with acute coronary syndrome (without coronary stent thrombosis, 22 patients with ST elevated myocardial infarction, 44 males, mean age 54 +/- 2 years) and underwent percutaneous coronary intervention in May 2011 formed group 2. Data were collected from all groups for 2 years. The RDW values were calculated from patients 1 month later at follow-up. Syntax scores were calculated for all the patients. The patients were also divided as low syntax score group and moderate-high syntax score group. Results: The patients in group 1 with stent thrombosis had significantly higher RDW level (13.85) than the patients in group 2 without stent thrombosis (12) (P < 0.001). In addition, in all study patients, the moderate-high syntax score group had significantly higher RDW level (13.6) than the low syntax score group (12.9) (P = 0.009). A positive correlation was determined between RDW and syntax scores (r = 0.204). Conclusion: RDW is a new marker of poor prognosis in coronary artery disease. Increased RDW level is correlated with angiographic severity of coronary artery disease, and RDW may be an important clinical marker of coronary stent thrombosis in patients undergoing coronary intervention.
dc.identifier.doi10.2147/IJGM.S109452
dc.identifier.endpage324
dc.identifier.issn1178-7074
dc.identifier.pmid27672339
dc.identifier.scopus2-s2.0-84992147646
dc.identifier.scopusqualityQ2
dc.identifier.startpage319
dc.identifier.urihttps://doi.org/10.2147/IJGM.S109452
dc.identifier.urihttps://hdl.handle.net/20.500.11776/9154
dc.identifier.volume9
dc.identifier.wosWOS:000390264400001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorTopçu, Birol
dc.language.isoen
dc.publisherDove Medical Press Ltd
dc.relation.ispartofInternational Journal of General Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectsyntax score
dc.subjectstent thrombosis
dc.subjectred cell distribution width
dc.subjectcoronary artery disease
dc.subjectLong-Term Mortality
dc.subjectPrognostic Marker
dc.subjectArtery-Disease
dc.subjectIntervention
dc.subjectRisk
dc.subjectMetaanalysis
dc.subjectPredictor
dc.titleClinical usefulness of red cell distribution width to angiographic severity and coronary stent thrombosis
dc.typeArticle

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