Adjuvant use of liquid alginate suspension for post-tonsillectomy morbidity: Double-blind randomized clinical trial of efficacy

Basit Öğe Kaydı
dc.authorscopusid7006196440
dc.authorscopusid26648338400
dc.authorscopusid57214434799
dc.contributor.authorYener, Murat
dc.contributor.authorGültekin, Erdoğan
dc.contributor.authorÖzdemir, İsmail
dc.date.accessioned2022-05-11T14:36:02Z
dc.date.available2022-05-11T14:36:02Z
dc.date.issued2009
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kulak Burun ve Boğaz Hastalıkları Ana Bilim Dalı
dc.description.abstractObjective: To evaluate the efficacy of liquid alginate suspension in alleviating post-tonsillectomy morbidity in adult patients. Methods: A prospective, double-blind, randomized, placebo-controlled study comparing the effect of liquid alginate suspension with placebo was performed on 40 patients who underwent tonsillectomy at Derince State Hospital, Kocaeli, Turkey. The patients were randomly chosen, and each used liquid alginate suspension four times daily or a placebo solution at the same regimen. Tonsillectomy was performed under general anesthesia by cold dissection and suture ligation. Patients were examined at postoperative days 1, 3, 5, and 7 for healing, instructed to note the amount of analgesics used, and asked to mark the visual analog score of throat pain every day for a week. Results: The study group had statistically significant lower pain scores at day 2 (P = 0.03). Study group required less analgesic than the control group during the study period, but the difference was statistically different only on day 2 (P = 0.003) day. Healing was statistically significant on day 5 (P = 0.03) in the study group. Conclusion: Use of the antireflux suspensions in patients undergoing tonsillectomy may be effective in reducing postoperative morbidity in adjunct with classic analgesics. © 2009 American Academy of Otolaryngology-Head and Neck Surgery Foundation.
dc.identifier.doi10.1016/j.otohns.2008.12.064
dc.identifier.endpage656
dc.identifier.issn0194-5998
dc.identifier.issue5en_US
dc.identifier.pmid19393405
dc.identifier.scopus2-s2.0-64749097681
dc.identifier.scopusqualityQ1
dc.identifier.startpage652
dc.identifier.urihttps://doi.org/10.1016/j.otohns.2008.12.064
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8346
dc.identifier.volume140
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorYener, Murat
dc.institutionauthorGültekin, Erdoğan
dc.institutionauthorÖzdemir, İsmail
dc.language.isoen
dc.relation.ispartofOtolaryngology - Head and Neck Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectalginic acid
dc.subjectgaviscon
dc.subjectibuprofen
dc.subjectplacebo
dc.subjectadult
dc.subjectantireflux operation
dc.subjectarticle
dc.subjectclinical article
dc.subjectclinical trial
dc.subjectcontrolled clinical trial
dc.subjectcontrolled study
dc.subjectdouble blind procedure
dc.subjectdrug efficacy
dc.subjectfemale
dc.subjecthealing
dc.subjecthuman
dc.subjectlaryngopharyngeal reflux
dc.subjectmale
dc.subjectpostoperative care
dc.subjectpostoperative pain
dc.subjectrandomized controlled trial
dc.subjectsore throat
dc.subjecttonsillectomy
dc.subjecttonsillitis
dc.subjectvisual analog scale
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAlginates
dc.subjectCase-Control Studies
dc.subjectChi-Square Distribution
dc.subjectDouble-Blind Method
dc.subjectFemale
dc.subjectGastroesophageal Reflux
dc.subjectGlucuronic Acid
dc.subjectHexuronic Acids
dc.subjectHumans
dc.subjectMale
dc.subjectPain Measurement
dc.subjectPlacebos
dc.subjectPostoperative Complications
dc.subjectProspective Studies
dc.subjectStatistics, Nonparametric
dc.subjectSuspensions
dc.subjectTonsillectomy
dc.subjectTonsillitis
dc.subjectTreatment Outcome
dc.titleAdjuvant use of liquid alginate suspension for post-tonsillectomy morbidity: Double-blind randomized clinical trial of efficacy
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
8346.pdf
Boyut:
426.63 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Tıp Fakültesi Koleksiyonu