The Effect of Testicular Torsion Duration on Testicular Steroidogenesis in the Rat Model

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dc.authorid0000-0001-6140-5181
dc.authorscopusid57216014831
dc.authorscopusid8416588900
dc.authorscopusid56008106600
dc.authorscopusid6603510624
dc.authorscopusid55782243700
dc.authorscopusid56616223400
dc.authorwosidYazici, Cenk Murat/AAA-4330-2020
dc.contributor.authorKurt, Ömer
dc.contributor.authorYazıcı, Cenk Murat
dc.contributor.authorGevher, Fetullah
dc.contributor.authorBalcı, Huriye
dc.contributor.authorYitik, Ali
dc.contributor.authorÖzkara, Hamdi
dc.date.accessioned2022-05-11T14:12:31Z
dc.date.available2022-05-11T14:12:31Z
dc.date.issued2016
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Üroloji Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Tıbbi Patoloji Ana Bilim Dalı
dc.description.abstractBackground: Testicular torsion is an emergency condition in which spermatogenesis may be irreversibly damaged. There have been controversial results about the effect of testicular torsion on steroidogenesis. We aimed at investigating the effect of testicular torsion on steroidogenesis. Material and Methods: A total of 40 adult male rats were divided into 4 groups. Left testicles were removed in all groups. Right testicles were torsioned and remained in the torsion position for 1, 3 and 5 h in study groups, whereas no torsion was performed in control. Serum luteinizing hormone (LH) and total testosterone (TT) levels were measured on the 3rd and 30th days of surgery and orchiectomy was performed on the 30th day of testicular torsion for histopathological evaluation. Results: TT levels of study groups were significantly lower than that of the control group on the 3rd day of torsion. LH of study groups was higher than that of the control group, but the difference was significant only in the 5 h torsion group. The total number of Leydig cells increased in 1- and 3-h groups, whereas it decreased in the 5-hour group. Conclusion: Testosterone production and Leydig cell functions significantly decreased after 5 h torsion in the rat model. The duration of torsion less than 5 h yielded partial dysfunction on steroidogenesis. (C) 2016 S. karger AG, Basel
dc.identifier.doi10.1159/000443969
dc.identifier.endpage364
dc.identifier.issn0042-1138
dc.identifier.issn1423-0399
dc.identifier.issue3en_US
dc.identifier.pmid27115502
dc.identifier.scopus2-s2.0-84973879206
dc.identifier.scopusqualityQ2
dc.identifier.startpage358
dc.identifier.urihttps://doi.org/10.1159/000443969
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5584
dc.identifier.volume97
dc.identifier.wosWOS:000385607700017
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKurt, Ömer
dc.institutionauthorYazıcı, Cenk Murat
dc.institutionauthorYitik, Ali
dc.language.isoen
dc.publisherKarger
dc.relation.ispartofUrologia Internationalis
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectTesticular torsion
dc.subjectTestosterone
dc.subjectLeydig cells
dc.subjectSteroidogenesis
dc.subjectEthylene Dimethane Sulfonate
dc.subjectLeydig-Cells
dc.subjectLuteinizing-Hormone
dc.subjectAdult-Rat
dc.subjectTestis
dc.subjectDestruction
dc.subjectSpermatogenesis
dc.titleThe Effect of Testicular Torsion Duration on Testicular Steroidogenesis in the Rat Model
dc.typeArticle

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