Transferring the protective effect of remote ischemic preconditioning on skin flap among rats by blood serum

Basit Öğe Kaydı
dc.authorid0000-0002-2470-3021
dc.authorid0000-0002-6396-3168
dc.authorid0000-0002-3053-9133
dc.authorscopusid16024976400
dc.authorscopusid55262663600
dc.authorscopusid14030178400
dc.authorscopusid15844109600
dc.authorscopusid35949526800
dc.authorwosidGunduz, Ozgur/A-2351-2016
dc.authorwosidSahin, Ertan/AAG-8999-2020
dc.authorwosidGÜNDÜZ, Özgür/AAH-8717-2019
dc.contributor.authorOrhan, Erkan
dc.contributor.authorGündüz, Özgür
dc.contributor.authorKaya, Oktay
dc.contributor.authorÖznur, Meltem
dc.contributor.authorŞahin, Ertan
dc.date.accessioned2022-05-11T14:36:55Z
dc.date.available2022-05-11T14:36:55Z
dc.date.issued2019
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Tıbbi Patoloji Ana Bilim Dalı
dc.description.abstractThe aim of this study was to show whether the protective effect of remote ischemic preconditioning (RIPC) on flaps can be transferred among different individuals with the transfusion of blood serum. Blood serum was taken from rats without any procedure (Group x), rats 1 hour (Group y) and 24 hours (Group z) after performing RIPC and the remaining rats were divided into six groups. While the random pattern skin flap was performed only in the back region in Group 1, and it was performed 1 hour (Group 2) and 24 hours (Group 3) after induction RIPC. Flap surgery was performed after the intravenous injection of serum obtained from Group x in Group 4, from Group y in Group 5, and from Group z in Group 6. After 7 days, the ratios of viable areas in the flaps of the remaining rats were calculated. When the viable area ratios in the flaps to the whole flap area were calculated, it was found out that the viable area ratios in Group 2 (61.6%), Group 3 (75.6%) and Group 6 (74.2%) were statistically significantly higher compared to Group 1 (51.5%), Group 4 (52.6%) and Group 5 (58.7%), that viable area ratios in Groups 3 and 6 were statistically significantly higher compared to Group 2, and that there was no difference between Groups 3 and 6. This study showed that RIPC forms a protective effect on the flaps and that this effect could be transferred among individuals with blood serum.
dc.identifier.doi10.1080/2000656X.2019.1582422
dc.identifier.endpage203
dc.identifier.issn2000-656X
dc.identifier.issn2000-6764
dc.identifier.issue4en_US
dc.identifier.pmid30888241
dc.identifier.scopus2-s2.0-85063076699
dc.identifier.scopusqualityQ2
dc.identifier.startpage198
dc.identifier.urihttps://doi.org/10.1080/2000656X.2019.1582422
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8483
dc.identifier.volume53
dc.identifier.wosWOS:000480623800002
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÖznur, Meltem
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofJournal of Plastic Surgery and Hand Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectRemote ischemic precondition
dc.subjectflap
dc.subjectblood serum
dc.subjectReperfusion Injury
dc.subjectMyocardial Protection
dc.subjectMuscle
dc.titleTransferring the protective effect of remote ischemic preconditioning on skin flap among rats by blood serum
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
8483.pdf
Boyut:
849.54 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Tıp Fakültesi Koleksiyonu