Simple Sensor Application: Determination of Electrochemical Properties of Carvedilol in CPE Based on Zinc Oxide Nanoparticles and Development of the Method for its Determination in Pharmaceutical Samples
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Tarih
2023
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
In this study, the electrochemical properties of carvedilol (CAR) were investigated by cy- clic voltammetry (CV) and square wave voltammetry (SWV) on carbon paste electrode modified with zinc oxide nanoparticles (ZnONP/CPE) in pH 8.0 Britton Robinson (BR) buffer. The adsorption characteristics of the molecule on the modified electrode and the electron number accompanying the electrode reaction were calculated. Furthermore, a new square wave anodic adsorptive stripping voltammetry (SWAAdSV) method was proposed for the determination of CAR in drug samples. The linear concentration range and detec- tion limit of the method were found to be 0.07 ?M–2.61 ?M and 0.09 ?M, respectively. To test the accuracy of the developed method, recovery studies of CAR in the pharma- ceutical sample were carried out. With the developed method, results with high reliability, reproducibility, accuracy, and precision were obtained for the determination of CAR in pharmaceutical samples.
Açıklama
Anahtar Kelimeler
Kaynak
Hittite Journal of Science and Engineering
WoS Q Değeri
Scopus Q Değeri
Cilt
10
Sayı
1
