Can the development of atrial fibrillation in patients with ischemic heart failure with low ejection fraction be predicted?

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dc.contributor.authorAlpsoy, Şeref
dc.contributor.authorErselcan, Kubilay
dc.contributor.authorAkyüz, Aydın
dc.contributor.authorÖzkaramanlı Gür, Demet
dc.contributor.authorTopuz, Sahin
dc.contributor.authorTopçu, Birol
dc.contributor.authorGüler, Niyazi
dc.date.accessioned2022-05-11T14:40:10Z
dc.date.available2022-05-11T14:40:10Z
dc.date.issued2020
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractOBJECTIVE: Our aim is to determine the triggering factors of paroxysmal atrial fibrillation (PAF) in ischemic heart failure (HF) patients with low ejection fraction (EF). METHODS: Sixty patients were included in this study. Echocardiography and 24-hours Holter monitoring were performed after measurement of serum NT-pro BNP concentration. The patients were classified into two groups concerning the occurrence of PAF on Holter recordings. Biochemical and echocardiographic parameters of patients with and without PAF were compared. RESULTS: PAF was detected in 28 (46%) patients. Patients with PAF demonstrated higher NT-pro BNP levels, mitral and aortic regurgitation velocities, E/A, E/E', pulmonary capillary wedge pressure, pulmonary artery systolic pressure, left atrial volume and volume indices. NT-pro BNP was established as the predictor of PAF (OR=1.23, 95% CI: 1.08-1.42; p=0.001).ROC analysis showed an NT-pro BNP value of 2188 pg/mL as cut-off value with 68% sensitivity and 84% specificity [Area under the ROC curve (AUC)=0.826, CI 95%: 0.724-0.927; p<0.001]. CONCLUSION: The triggering factors for AF are increased intracardiac pressures, left atrial dilatation and increased wall tension. As an indicator of increased wall tension, elevated levels of NT-pro BNP predict the development of PAF.
dc.identifier.doi10.14744/nci.2019.07078
dc.identifier.endpage24
dc.identifier.issn2148-4902
dc.identifier.issue1en_US
dc.identifier.pmid32232199
dc.identifier.startpage18
dc.identifier.urihttps://doi.org/10.14744/nci.2019.07078
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8886
dc.identifier.volume7
dc.identifier.wosWOS:000514812200004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.institutionauthorAlpsoy, Şeref
dc.institutionauthorAkyüz, Aydın
dc.institutionauthorÖzkaramanlı Gür, Demet
dc.institutionauthorTopuz, Sahin
dc.institutionauthorGüler, Niyazi
dc.language.isoen
dc.publisherKare Publ
dc.relation.ispartofNorthern Clinics of Istanbul
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAtrial fibrillation
dc.subjectheart failure
dc.subjectischemic
dc.subjectlow ejection fraction
dc.subject2016 Esc Guidelines
dc.subjectNatriuretic Peptide
dc.subjectRisk-Factors
dc.subjectAssociation
dc.subjectCollaboration
dc.subjectManagement
dc.subjectSociety
dc.titleCan the development of atrial fibrillation in patients with ischemic heart failure with low ejection fraction be predicted?
dc.typeArticle

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