Is Overweight a Risk of Early Atherosclerosis in Childhood?

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dc.authorid0000-0002-4060-0583
dc.authorid0000-0003-0771-2505
dc.authorid0000-0002-5630-3399
dc.authorwosidDonma, Mustafa Metin/ABF-2169-2021
dc.authorwosidTopçu, Birol/ABA-6104-2020
dc.authorwosidNALBANTOGLU, BURCIN/A-5386-2018
dc.contributor.authorAlpsoy, Şeref
dc.contributor.authorAkyüz, Aydın
dc.contributor.authorAkkoyun, Dursun Çayan
dc.contributor.authorNalbanto?lu, Burçin
dc.contributor.authorTopçu, Birol
dc.contributor.authorTülübaş, Feti
dc.contributor.authorDonma, Mustafa Metin
dc.date.accessioned2022-05-11T14:09:56Z
dc.date.available2022-05-11T14:09:56Z
dc.date.issued2020
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Biyoistatistik Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.description.abstractWe measured brachial artery flow-mediated dilatation (FMD) and common carotid intima-media thickness (cIMT) in overweight (n = 67) and normal weight children (n = 115, controls). Age at examination ranged from 72 to 182 months (mean 123 +/- 27). Compared to controls, the overweight children had increased weight, waist and hip circumference, systolic and diastolic blood pressures (all P < .001), right and left mean cIMT (mm; 0.58 [0.42-0.68] vs 0.44 [0.3-0.64], P < .001 and 0.56 [0.32-0.70] vs 0.44 [0.3-0.60], P < .001), respectively, and decreased FMD (%; 6.25 [3.33-19.05] vs 7.69 [3.45-16], P < .001). The cIMT and FMD were closely related to the serum insulin concentrations. Age, waist circumferences, and serum triglycerides were independent predictive risk factors for increased cIMT, and fasting glucose and BMI were independent predictive variables for decreased FMD. Overweight children are also potentially at risk of early atherosclerosis as much as obese children.
dc.identifier.doi10.1177/0003319713476134
dc.identifier.endpage443
dc.identifier.issn0003-3197
dc.identifier.issn1940-1574
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-84884686468
dc.identifier.scopusqualityQ2
dc.identifier.startpage438
dc.identifier.urihttps://doi.org/10.1177/0003319713476134
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5211
dc.identifier.volume71
dc.identifier.wosWOS:000523733400007
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorAlpsoy, Şeref
dc.institutionauthorAkyüz, Aydın
dc.institutionauthorAkkoyun, Dursun Çayan
dc.institutionauthorNalbanto?lu, Burçin
dc.institutionauthorTopçu, Birol
dc.institutionauthorTülübaş, Feti
dc.institutionauthorDonma, Mustafa Metin
dc.language.isoen
dc.publisherSage Publications Inc
dc.relation.ispartofAngiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectoverweight
dc.subjectchildhood
dc.subjectperipheral arterial disease
dc.subjectflow-mediated dilatation
dc.subjectcarotid intima-media thickness
dc.subjectIntima-Media Thickness
dc.subjectEndothelial Dysfunction
dc.subjectBrachial-Artery
dc.subjectChildren
dc.subjectObesity
dc.subjectVasodilation
dc.subjectUltrasound
dc.subjectStatement
dc.subjectStiffness
dc.subjectSociety
dc.titleIs Overweight a Risk of Early Atherosclerosis in Childhood?
dc.typeArticle

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