An evaluation of the effect of biodegradable stents on restenosis in the treatment of peripheral arterial lesions

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dc.authorscopusid56029407300
dc.authorscopusid39361319600
dc.authorscopusid7004418045
dc.authorscopusid23391660500
dc.authorscopusid6602958747
dc.authorwosidVural, Ahmet Hakan/AAF-7810-2021
dc.authorwosid/AAD-1829-2020
dc.contributor.authorAkgül, Engin
dc.contributor.authorErdolu, Burak
dc.contributor.authorVural, Ahmet Hakan
dc.contributor.authorYümün, Gündüz
dc.contributor.authorÖzyazıcıoğlu, Ahmet Fatih
dc.date.accessioned2022-05-11T14:36:00Z
dc.date.available2022-05-11T14:36:00Z
dc.date.issued2017
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kalp ve Damar Cerrahisi Ana Bilim Dalı
dc.description.abstractBackground: This study aims to investigate possible factors which increase the risk of restenosis in patients undergoing biodegradable stenting. Methods: A total of 45 patients (39 males, 6 females; mean age 58 +/- 7.2 years; range 41 to 71 years) in whom femoral artery occlusion was treated by biodegradable stents between January 2010 and December 2012 were retrospectively analyzed. The Ankle Brachial Index scores were recorded at baseline and at one week, one month, sixth month, and one year, postoperatively. The patients were divided into two groups according to the postoperative six-month arterial Doppler ultrasonography findings: group 1 (n=10) had no flow or monophasic flow, and group 2 (n=35) had biphasic or triphasic flow pattern. Additional treatments after postoperative sixth month in group 1 were also noted. Results: Restenosis developed in 10 patients (22%) within postoperative six months. Although the number of smokers was significantly higher in group 1 (p=0.048), no relationship was found between diabetes and restenosis. The presence of coronary artery disease (p=0.049) and elevated triglycerides (p=0.035) were found to be risk factors of restenosis. More than one stenting was a predisposing factor of restenosis (p=0.033). Conclusion: Our study results show that being under the age of 60 years, elevated triglyceride levels, and smoking are the risk factors for restenosis in those with peripheral arterial disease. In addition, the presence of coronary artery disease increases the risk of restenosis. However, biodegradable stent implantation yielded unsatisfactory results in those with long-segment stenosis and advanced disease; therefore, we recommend further large-scale studies to improve the procedural outcomes.
dc.identifier.doi10.5606/tgkdc.dergisi.2017.13351
dc.identifier.endpage208
dc.identifier.issn1301-5680
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85018815450
dc.identifier.scopusqualityQ3
dc.identifier.startpage203
dc.identifier.urihttps://doi.org/10.5606/tgkdc.dergisi.2017.13351
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8335
dc.identifier.volume25
dc.identifier.wosWOS:000402620300006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorYümün, Gündüz
dc.language.isotr
dc.publisherBaycinar Medical Publ-Baycinar Tibbi Yayincilik
dc.relation.ispartofTurk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBiodegradable stent
dc.subjectperipheral arterial disease
dc.subjectstent restenosis
dc.subjectSuperficial Femoral-Artery
dc.subjectRisk-Factors
dc.subjectDisease
dc.subjectAngioplasty
dc.subjectOutcomes
dc.subjectLesions
dc.titleAn evaluation of the effect of biodegradable stents on restenosis in the treatment of peripheral arterial lesions
dc.title.alternativePeriferik arteriyel lezyonlarin tedavisinde biyoeriyebilen stentlerin restenoz üzerine etkisinin değerlendirilmesi]
dc.typeArticle

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