Amiodarone induced thyrotoxicosis may not respond to therapeutic plasma exchange like patients with graves' disease: A report of two cases and literature review

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dc.contributor.authorYıldız, İsmail
dc.contributor.authorElbüken, Gülşah
dc.contributor.authorAtasever, Tugay
dc.contributor.authorGürdal, Sibel Özkan
dc.contributor.authorZuhur, Sayid Shafi
dc.date.accessioned2022-05-11T14:39:50Z
dc.date.available2022-05-11T14:39:50Z
dc.date.issued2019
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractThe achievement of euthyroid state has been suggested in patients with thyrotoxicosis undergoing surgery to reduce the risk of thyroid storm. However, euthyroid state could not always be achieved by antithyroid drugs. Therefore, therapeutic plasma exchange (TPE) is an option in this condition. A 58-year-old male patient with a history of type-2 diabetes using 200 mg amiodarone per day, admitted for diabetic ketoacidosis (DKA), induced by thyrotoxicosis. with palpitation, sweating, polyuria, and polydipsia. Euthyroid state could not be achieved, despite all apropriate treatments for thyrotoxicosis. Therefore, preparation with TPE followed by total thyroidectomy was planned. A 35% decrease in fT3 (free T3) and fT4 (free T4) levels were achieved, after two sessions of TPE. A 74-year-old male patient, admitted for acute anterior myocardial infarction (AMI) induced by thyrotoxicosis due to Graves’ disease. Multiple vessel disease was detected on primer percutanous coronary angiography, and an emergency coronary artery bypass grafting (CABG) was planned. Therefore, preperation with TPE was planned before surgery. A substential decrease in fT4 and fT3 levels (45% and 72%, respectively) levels were achieved, after one session of TPE. Most of the studies evaluating the efficacy of TPE in patients with thyrotoxicosis are including patients with Graves’ disease and toxic multinodular goiter, and TPE was indicated as an effective option for preparation of these patients for surgery. However, as presented in case 1, TPE may not be effective in amiodarone induced thyrotoxicosis (AIT) as in cases with thyrotoxicosis due to Graves’ disease.
dc.identifier.doi10.5455/medscience.2018.07.8954
dc.identifier.endpage236
dc.identifier.issn2147-0634
dc.identifier.issn2147-0634
dc.identifier.issue1en_US
dc.identifier.startpage233
dc.identifier.trdizinidTXpBNE5URTFOUT09
dc.identifier.urihttps://doi.org/10.5455/medscience.2018.07.8954
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpBNE5URTFOUT09
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8755
dc.identifier.volume8
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorYıldız, İsmail
dc.institutionauthorElbüken, Gülşah
dc.institutionauthorAtasever, Tugay
dc.institutionauthorGürdal, Sibel Özkan
dc.institutionauthorZuhur, Sayid Shafi
dc.language.isoen
dc.relation.ispartofMedicine Science
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBiyoloji
dc.subjectAlerji
dc.subjectAnatomi ve Morfoloji
dc.subjectAndroloji
dc.subjectAnestezi
dc.subjectOdyoloji ve Konuşma-Dil Patolojisi
dc.subjectBiyokimya ve Moleküler Biyoloji
dc.subjectBiyofizik
dc.subjectBiyoteknoloji ve Uygulamalı Mikrobiyoloji
dc.subjectKalp ve Kalp Damar Sistemi
dc.subjectHücre Biyolojisi
dc.subjectKlinik Nöroloji
dc.subjectYoğun Bakım
dc.subjectTıp
dc.subjectDermatoloji
dc.subjectAcil Tıp
dc.subjectEndokrinoloji ve Metabolizma
dc.subjectGastroenteroloji ve Hepatoloji
dc.subjectGeriatri ve Gerontoloji
dc.subjectSağlık Bilimleri ve Hizmetleri
dc.subjectHematoloji
dc.subjectİmmünoloji
dc.subjectEnfeksiyon Hastalıkları
dc.subjectTamamlayıcı ve Entegre Tıp
dc.subjectTıbbi Etik
dc.subjectTıbbi İnformatik
dc.subjectTıbbi Laboratuar Teknolojisi
dc.subjectGenel ve Dahili Tıp
dc.subjectAdli Tıp
dc.subjectTıbbi Araştırmalar Deneysel
dc.subjectMikrobiyoloji
dc.subjectNörolojik Bilimler
dc.subjectKadın Hastalıkları ve Doğum
dc.subjectOnkoloji
dc.subjectGöz Hastalıkları
dc.subjectOrtopedi
dc.subjectKulak
dc.subjectBurun
dc.subjectBoğaz
dc.subjectPatoloji
dc.subjectPediatri
dc.subjectPeriferik Damar Hastalıkları
dc.subjectFizyoloji
dc.subjectTemel Sağlık Hizmetleri
dc.subjectPsikiyatri
dc.subjectHalk ve Çevre Sağlığı
dc.subjectRadyoloji
dc.subjectNükleer Tıp
dc.subjectTıbbi Görüntüleme
dc.subjectRehabilitasyon
dc.subjectSolunum Sistemi
dc.subjectRomatoloji
dc.subjectSpor Bilimleri
dc.subjectCerrahi
dc.subjectTransplantasyon
dc.subjectTropik Tıp
dc.subjectÜroloji ve Nefroloji
dc.titleAmiodarone induced thyrotoxicosis may not respond to therapeutic plasma exchange like patients with graves' disease: A report of two cases and literature review
dc.typeArticle

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