Investigation of Some Azo Dyes by QSAR Method and Acute Toxicity Test with Daphnia Magna

dc.contributor.authorKarabulut, Yasemin Keşkek
dc.contributor.authorGurkan, Yelda Yalcin
dc.date.accessioned2024-10-29T17:50:22Z
dc.date.available2024-10-29T17:50:22Z
dc.date.issued2023
dc.departmentTekirdağ Namık Kemal Üniversitesi
dc.description.abstractAzo dyes represent the most important class of textile dyes. Biotransformation of azo dyes can release aromatic amines. It is well known that some aromatic amines have genotoxic and/or carcinogenic properties. In this study, it was aimed to investigate the effects of azo dyes, which are composed of aromatic amines, and are widely used in the textile industry, on the environment using acute water toxicity test. The acute water toxicity test using Daphnia Magna was investigated experimentally and theoretically. The OECD QSAR Toolbox program, which has recently attracted attention in theoretical studies and is also used in international regulations, has been preferred. As a result of the studies, it was seen that the experimental and theoretical results gave parallel results. This study showed that theoretical studies can be substituted for experimental studies in order to reduce cost, time, and animal mortality in acute toxicity tests on Daphnia Magna. In addition, according to the results of this study, it was found by experimental and theoretical methods that Basic Yellow 28, Disperse Blue 291, and Disperse Brown 27-1 azo dye are ecotoxicologically toxic.
dc.identifier.doi10.21597/jist.1214772
dc.identifier.endpage1119
dc.identifier.issn2146-0574
dc.identifier.issn2536-4618
dc.identifier.issue2en_US
dc.identifier.startpage1110
dc.identifier.trdizinid1181448
dc.identifier.urihttps://doi.org/10.21597/jist.1214772
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1181448
dc.identifier.urihttps://hdl.handle.net/20.500.11776/12956
dc.identifier.volume13
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofIğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectQSAR
dc.subjectAzo Dyes
dc.subjectEcotoxicology
dc.subjectAromatic amines
dc.subjectTheoretical chemistry
dc.subjectDaphnia Amgna
dc.titleInvestigation of Some Azo Dyes by QSAR Method and Acute Toxicity Test with Daphnia Magna
dc.typeArticle

Dosyalar