Obstructive sleep apnea syndrome and erectile dysfunction: does long term continuous positive airway pressure therapy improve erections?
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Dosyalar
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Makerere Univ, Fac Med
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objectives: The aim of this age-matched, controlled, prospective clinical study was to investigate frequency and degree of erectile dysfunction (ED) in patients with obstructive sleep apnea syndrome (OSAS) and to evaluate the results of only continuous positive airway pressure (CPAP) therapy on ED in patients with OSAS. Materials and Methods: A total of 90 patients were evaluated for potential OSAS. They were given an International Index of Erectile Function questionnaire (IIEF) and Beck Depression Inventory. Sixty-two patients with the diagnosis of OSAS were regarded as study group. Twenty-eight patients in whom the OSAS was excluded, were regarded as the control group. Biochemical and hormonal laboratory evaluation were performed. Then all patients underwent a full-night in laboratory polysomnography examination. The degree of OSAS were evaluated by an expert from chest diseases department. Results: When compared to the control group, a decrease in IIEF-5 scores was found in patients with OSAS. However, this decrease was not statistically significant. After 3 months of CPAP usage in patients with mild to moderate and severe degree OSAS, improvement in IIEF-5 scores was statistically significant. Mean value of IIEF-5 score was 16.63 +/- 5.91 before CPAP and were improved up to 20.92 +/- 6.79 (P=0.001). Conclusion: It is not certainly possible to say that OSAS is clearly associated with ED. However, after 3 months of regular CPAP usage, ED complaints in patients with OSAS might improve positively. Trials with larger series may give more conclusive data.
Açıklama
Anahtar Kelimeler
Sleep disorder, erectile dysfunction, obstructive sleep apnea syndrome, CPAP, Sexual Function, Cpap Treatment, Men, Disorders, Population, Prevalence, Sildenafil, Mechanisms
Kaynak
African Health Sciences
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
15
Sayı
1
