The impact of COVID-19 on familial Mediterranean fever: a nationwide study

Basit Öğe Kaydı
dc.authorid0000-0003-3584-2788
dc.authorid0000-0003-4567-8133
dc.authorid0000-0001-8142-913X
dc.authorid0000-0003-0966-0075
dc.authorid0000-0003-4838-1650
dc.authorid0000-0001-8287-2264
dc.authorid0000-0002-4390-7169
dc.authorscopusid23094547900
dc.authorscopusid28168097700
dc.authorscopusid7004099237
dc.authorscopusid56673866600
dc.authorscopusid56732926400
dc.authorscopusid15073854500
dc.authorscopusid15127959300
dc.authorwosidDuruoz, Mehmet Tuncay/I-2307-2016
dc.authorwosidYurdakul, Ozan Volkan/F-5266-2019
dc.authorwosidşen, nesrin/ABI-6368-2020
dc.authorwosidkarahan, ali yavuz/E-4481-2017
dc.contributor.authorGunendi, Zafer
dc.contributor.authorYurdakul, Fatma Gül
dc.contributor.authorBodur, Hatice
dc.contributor.authorCengiz, Ahmet Kivanc
dc.contributor.authorUçar, Ülkü
dc.contributor.authorCay, Hasan Fatih
dc.contributor.authorAtaman, Şebnem
dc.contributor.authorNayimoğlu, Mehmet
dc.contributor.authorSarıfakıoğlu, Ayşe Banu
dc.date.accessioned2022-05-11T14:39:46Z
dc.date.available2022-05-11T14:39:46Z
dc.date.issued2021
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Fizik Tedavi ve Rehabilitasyon Ana Bilim Dalı
dc.description.abstractThe study aimed to evaluate the impact of the coronavirus disease 2019 (COVID-19) in patients with familial Mediterranean fever (FMF) and to assess the relationships between FMF characteristics and severe COVID-19 outcomes such as hospitalization. The study was planned within a national network of 21 different centers. Demographics, FMF-related clinical and genetic characteristics, and COVID-19 outcomes were obtained. A total of 822 patients with FMF (mean age of 36 years) were included in the study. Fifty-nine of them (7%) had a COVID-19 diagnosis confirmed by real-time PCR test or chest CT findings. Most FMF patients with COVID-19 (58) had mild and moderate disease activity. All patients were on colchicine treatment. However, 8 of them (13.6%) were not compliant with colchicine use and 9 of them (15.3%) were colchicine resistant. Twelve FMF patients with COVID-19 were hospitalized. There were 4 patients requiring oxygen support. COVID-19 related complications were observed in 2 patients (1 thromboembolism, 1 acute respiratory distress syndrome). Hospitalized COVID-19 patients with FMF were older than non-hospitalized patients (median ages: 51 and 31 years, respectively; p: 0.002). Other FMF-related characteristics were similar between the groups. FMF-related characteristics were not found to be associated with poor outcomes in COVID-19. Thus, FMF may not be a risk factor for poor COVID-19 outcomes.
dc.identifier.doi10.1007/s00296-021-04892-6
dc.identifier.endpage1455
dc.identifier.issn0172-8172
dc.identifier.issn1437-160X
dc.identifier.issue8en_US
dc.identifier.pmid34032894
dc.identifier.scopus2-s2.0-85106463983
dc.identifier.scopusqualityQ2
dc.identifier.startpage1447
dc.identifier.urihttps://doi.org/10.1007/s00296-021-04892-6
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8705
dc.identifier.volume41
dc.identifier.wosWOS:000654089100002
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorNayimoğlu, Mehmet
dc.institutionauthorSarıfakıoğlu, Ayşe Banu
dc.language.isoen
dc.publisherSpringer Heidelberg
dc.relation.ispartofRheumatology International
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCOVID-19
dc.subjectFamilial Mediterranean fever
dc.subjectRheumatic diseases
dc.subjectColchicine
dc.subjectHospitalization
dc.subjectPoor outcomes
dc.titleThe impact of COVID-19 on familial Mediterranean fever: a nationwide study
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
8705.pdf
Boyut:
637.2 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Tıp Fakültesi Koleksiyonu