Community-acquired Lower Urinary Tract Infections: Etiology, Antimicrobial Resistance, and Treatment Results in Female Patients

Basit Öğe Kaydı
dc.authorid0000-0003-2440-7529
dc.authorscopusid6602163658
dc.authorscopusid57203430154
dc.authorscopusid57202750841
dc.authorscopusid57191621540
dc.authorscopusid56079827600
dc.authorscopusid55664492500
dc.authorwosidKARAALİ, Rıdvan/AAQ-1018-2020
dc.contributor.authorErdem, İlknur
dc.contributor.authorKaraali, Rıdvan
dc.contributor.authorArdic, Enes
dc.contributor.authorOmar, Şenay Elbasan
dc.contributor.authorMutlu, Reyhan
dc.contributor.authorTopkaya, Aynur Eren
dc.date.accessioned2022-05-11T14:14:07Z
dc.date.available2022-05-11T14:14:07Z
dc.date.issued2018
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Mikrobiyoloji Ana Bilim Dalı
dc.description.abstractBackground/Purpose: Most community-acquired urinary tract infections (UTIs) are usually treated empirically. The knowledge of antibiotic resistance patterns of the microorganisms causing UTI is essential for defining the empirical treatment. Objective: The aim of the present study is to determine the distribution of bacterial strains isolated from lower UTIs and their resistance patterns against commonly used antimicrobial agents and treatment results in female patients. Subjects and Methods: This is a retrospective analysis of medical case records of 90 female patients with lower UTI for a period of 4 years from January 2013 to December 2016 in a tertiary care hospital in the Trakya region of Turkey. Results: The most common causative agent was Escherichia coli (66.6% of cases) followed by Klebsiella pneumoniae (16.6%). Fosfomycin was the most active agent against E. coli (resistant isolates: 5.5%), followed by nitrofurantoin (resistant isolates: 7.4%). Extended-spectrum beta-lactamases (ESBLs) production was observed in 29 (32.2%) isolates (22 in E. coli, 6 in K. pneumoniae, and 1 in Enterobacter spp.). The antimicrobial resistance rates among ESBL-producing E. coli isolates for trimethoprim-sulfamethoxazole, ciprofloxacin, fosfomycin, and nitrofurantoin were 77.7%, 72.7%, 13.6%, and 18.2%, respectively (P < 0.05). The estimated microbiological eradication rates for nitrofurantoin and fosfomycin were 89.7% and 83.8%, respectively. Conclusions: The results of the present study indicate that nitrofurantoin and fosfomycin may be considered for empirical therapy of lower UTIs in Trakya region of Turkey.
dc.identifier.doi10.4103/jgid.jgid_86_17
dc.identifier.endpage132
dc.identifier.issn0974-777X
dc.identifier.issn0974-8245
dc.identifier.issue3en_US
dc.identifier.pmid30166811
dc.identifier.scopus2-s2.0-85051718196
dc.identifier.scopusqualityQ3
dc.identifier.startpage129
dc.identifier.urihttps://doi.org/10.4103/jgid.jgid_86_17
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5794
dc.identifier.volume10
dc.identifier.wosWOS:000441828700005
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorErdem, İlknur
dc.institutionauthorKaraali, Rıdvan
dc.institutionauthorArdic, Enes
dc.institutionauthorOmar, Şenay Elbasan
dc.institutionauthorMutlu, Reyhan
dc.institutionauthorTopkaya, Aynur Eren
dc.language.isoen
dc.publisherWolters Kluwer Medknow Publications
dc.relation.ispartofJournal of Global Infectious Diseases
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAntimicrobial resistance
dc.subjectetiology
dc.subjectfosfomycin
dc.subjectnitrofurantoin
dc.subjecturinary tract infection
dc.subjectEscherichia-Coli
dc.subjectSusceptibility
dc.subjectNitrofurantoin
dc.subjectFosfomycin
dc.subjectEpidemiology
dc.subjectManagement
dc.titleCommunity-acquired Lower Urinary Tract Infections: Etiology, Antimicrobial Resistance, and Treatment Results in Female Patients
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
5794.pdf
Boyut:
395.22 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Tıp Fakültesi Koleksiyonu