Vitamin D levels in white coat and sustained hypertension

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dc.authorscopusid6505680586
dc.authorscopusid16315021800
dc.authorscopusid26532378600
dc.authorscopusid55317577700
dc.authorscopusid37058172000
dc.authorscopusid8514414100
dc.authorwosidAlpsoy, Seref/Z-1808-2018
dc.contributor.authorAlpsoy, Şeref
dc.contributor.authorAkyüz, Aydın
dc.contributor.authorAkkoyun, Dursun Çayan
dc.contributor.authorÖzkaramanlı Gür, Demet
dc.contributor.authorTopçu, Birol
dc.contributor.authorTülübaş, Feti
dc.date.accessioned2022-05-11T14:10:16Z
dc.date.available2022-05-11T14:10:16Z
dc.date.issued2016
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Biyoistatistik Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.description.abstractObjective The plasma levels of vitamin D in patients with white coat hypertension (WCHT) have not been studied previously. The aim of this study was to evaluate vitamin D levels in WCHT and compare with sustained hypertension (SHT) and with normotension (NT). Patients and methods Fifty-three normotensive, 42 WCHT, and 59 SHT patients were recruited in this study. The participants were matched for age, sex, and BMI. The vitamin D levels were determined using the electrochemiluminescence immunoassay method. Results Plasma vitamin D levels were significantly lower in SHT than in the WCHT and NT groups (26.4 +/- 4.9, 34.3 +/- 3.6, and 36 +/- 5 ng/ml, respectively), and were similar in the WCHT and NT groups. There was a negative correlation between vitamin D levels and blood pressure parameters such as clinic systolic blood pressure (SBP), clinic diastolic blood pressure (DBP), 24-h SBP, 24-h DBP, daytime SBP, daytime DBP, night-time SBP, and night-time DBP (r=-0.554, -0.419, -0.629, -0.427, -0.559, -0.534, -0.607, -0.462, respectively, and all P<0.001) in the entire study group. Clinic SBP (B +/- SE=-0.97 +/- 0.037, P = 0.009) and 24-h SBP (B +/- SE=-0.138 +/- 0.055, P = 0.013) were identified as predictors for vitamin D levels in the entire study group. Conclusion Our data show that sustained hypertensive patients have lower vitamin D levels than white coat hypertensive and normotensive individuals. White coat hypertensive patients without other cardiovascular risk factors have higher vitamin D levels than sustained hypertensive patients, suggesting that they have a lower cardiovascular risk. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved.
dc.identifier.doi10.1097/MBP.0000000000000171
dc.identifier.endpage135
dc.identifier.issn1359-5237
dc.identifier.issn1473-5725
dc.identifier.issue3en_US
dc.identifier.pmid26735704
dc.identifier.scopus2-s2.0-84953285214
dc.identifier.scopusqualityQ2
dc.identifier.startpage131
dc.identifier.urihttps://doi.org/10.1097/MBP.0000000000000171
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5346
dc.identifier.volume21
dc.identifier.wosWOS:000376282100001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAlpsoy, Şeref
dc.institutionauthorAkyüz, Aydın
dc.institutionauthorAkkoyun, Dursun Ceyhan
dc.institutionauthorÖzkaramanlı Gür, Demet
dc.institutionauthorTopçu, Birol
dc.institutionauthorTülübaş, Feti
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofBlood Pressure Monitoring
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectambulatory blood pressure monitoring
dc.subject25-hydroxyvitamin D
dc.subjectwhite coat hypertension
dc.subjectIsolated Systolic Hypertension
dc.subject10-Year Follow-Up
dc.subjectBlood-Pressure
dc.subjectMasked Hypertension
dc.subjectInternational Database
dc.subjectRisk-Factor
dc.subject25-Hydroxyvitamin-D
dc.subjectMetaanalysis
dc.subjectPrognosis
dc.subjectEvents
dc.titleVitamin D levels in white coat and sustained hypertension
dc.typeArticle

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