Evaluation of immunization status in patients with cerebral palsy: a multicenter CP-VACC study

dc.authorid0000-0002-5902-3501
dc.authorid0000-0002-5389-5616
dc.authorscopusid57209256022
dc.authorscopusid36994455700
dc.authorscopusid25623200200
dc.authorscopusid53879580300
dc.authorscopusid6602402327
dc.authorscopusid57191406289
dc.authorscopusid13205268800
dc.contributor.authorBozkaya-Yılmaz, Sema
dc.contributor.authorKaradağ Öncel, Eda
dc.contributor.authorOlgaç-Dündar, Nihal
dc.contributor.authorGencpinar, Pınar
dc.contributor.authorSarıoğlu, Berrak
dc.contributor.authorArican, Pınar
dc.contributor.authorÇavuşoğlu, Dilek
dc.contributor.authorGürbüz, Gürkan
dc.date.accessioned2022-05-11T14:37:17Z
dc.date.available2022-05-11T14:37:17Z
dc.date.issued2022
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.description.abstractChildren with chronic neurological diseases, including cerebral palsy (CP), are especially susceptible to vaccine-preventable infections and face an increased risk of severe respiratory infections and decompensation of their disease. This study aims to examine age-appropriate immunization status and related factors in the CP population of our country. This cross-sectional prospective multicentered survey study included 18 pediatric neurology clinics around Turkey, wherein outpatient children with CP were included in the study. Data on patient and CP characteristics, concomitant disorders, vaccination status included in the National Immunization Program (NIP), administration, and influenza vaccine recommendation were collected at a single visit. A total of 1194 patients were enrolled. Regarding immunization records, the most frequently administrated and schedule completed vaccines were BCG (90.8%), hepatitis B (88.9%), and oral poliovirus vaccine (88.5%). MMR was administered to 77.3%, and DTaP-IPV-HiB was administered to 60.5% of patients. For the pneumococcal vaccines, 54.1% of children received PCV in the scope of the NIP, and 15.2% of children were not fully vaccinated for their age. The influenza vaccine was administered only to 3.4% of the patients at any time and was never recommended to 1122 parents (93.9%). In the patients with severe (grades 4 and 5) motor dysfunction, the frequency of incomplete/none vaccination of hepatitis B, BCG, DTaP-IPV-HiB, OPV, and MMR was statistically more common than mild to moderate (grades 1-3) motor dysfunction (p = 0.003, p < 0.001, p < 0.001, p < 0.00, and p < 0.001, respectively). Physicians' influenza vaccine recommendation was higher in the severe motor dysfunction group, and the difference was statistically significant (p = 0.029). Conclusion: Children with CP had lower immunization rates and incomplete immunization programs. Clinicians must ensure children with CP receive the same preventative health measures as healthy children, including vaccines.
dc.identifier.doi10.1007/s00431-021-04219-4
dc.identifier.endpage391
dc.identifier.issn0340-6199
dc.identifier.issn1432-1076
dc.identifier.issue1en_US
dc.identifier.pmid34355277
dc.identifier.scopus2-s2.0-85111859160
dc.identifier.scopusqualityQ1
dc.identifier.startpage383
dc.identifier.urihttps://doi.org/10.1007/s00431-021-04219-4
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8644
dc.identifier.volume181
dc.identifier.wosWOS:000681539900002
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorGürbüz, Gürkan
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofEuropean Journal of Pediatrics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCerebral palsy
dc.subjectImmunization status
dc.subjectRespiratory infections
dc.subjectPneumococcus
dc.subjectInfluenza
dc.subjectInfluenza Vaccination
dc.subjectChildren
dc.subjectCoverage
dc.subjectClassification
dc.subjectTimeliness
dc.subjectDefinition
dc.subjectRisk
dc.titleEvaluation of immunization status in patients with cerebral palsy: a multicenter CP-VACC study
dc.typeArticle

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